Results 161 to 170 of about 260,481 (286)

Antiviral regulator TRIM25 as a prognostic marker of better survival in Merkel cell carcinoma: Association with MCPyV status

open access: yesInternational Journal of Cancer, EarlyView.
What's New? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt   +6 more
wiley   +1 more source

The IPD-IMGT/HLA database: recent developments in sequence submission. [PDF]

open access: yesNucleic Acids Res
Barker DJ   +7 more
europepmc   +1 more source

Efficacy and immunogenic effects of Tumor Treating Fields (TTFields) in preclinical models of pancreatic ductal adenocarcinoma, with and without gemcitabine/nab‐paclitaxel

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Adaptive immune responses are typically limited in pancreatic ductal adenocarcinoma, resulting in minimal efficacy of immune checkpoint inhibitors. Tumor Treating Fields (TTFields) therapy, which uses low‐intensity intermediate‐frequency electric fields to disrupt cancer cell processes, has been approved for certain cancers.
Tal Kan   +21 more
wiley   +1 more source

Quadruple-drug induction therapy in highly sensitized patients [PDF]

open access: yes, 1988
Abendroth, D.   +3 more
core   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

open access: yesInterdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang   +4 more
wiley   +1 more source

Intratumoral bacteria engineered for tumor therapy

open access: yesInterdisciplinary Medicine, EarlyView.
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang   +7 more
wiley   +1 more source

Placenta‐derived extracellular vesicles: Signal messengers shuttling across the maternal‐fetal barrier

open access: yesInterdisciplinary Medicine, EarlyView.
In normal pregnancy, PEVs help maintain maternal–fetal immune tolerance while enabling controlled immune activation, promote endothelial migration, and support trophoblast invasion and syncytialization, strengthening antimicrobial defense. In pregnancy‐related disorders, dysregulated PEV signaling may drive endothelial dysfunction and hypertension, BBB
Jiale Du   +5 more
wiley   +1 more source

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