Results 181 to 190 of about 211,384 (368)

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Per‐ and polyfluoroalkyl substances activate UPR pathway, induce steatosis and fibrosis in liver cells

Environmental Toxicology, Volume 38, Issue 1, Page 225-242, January 2023., 2023
Abstract Per‐ and polyfluoroalkyl substances (PFAS), which include perfluorooctanoic acid (PFOA), heptafluorobutyric acid (HFBA), and perfluorotetradecanoic acid (PFTA), are commonly occurring organic pollutants. Exposure to PFAS affects the immune system, thyroid and kidney function, lipid metabolism, and insulin signaling and is also involved in the ...
Qi Qi, Suryakant Niture, Sashi Gadi, Elena Arthur, John Moore, Keith E. Levine, Deepak Kumar   +6 more
wiley   +1 more source

THE MOLECULAR INDIVIDUALITY OF DIFFERENT MOUSE H-2 HISTOCOMPATIBILITY SPECIFICITIES DETERMINED BY SINGLE GENOTYPES

, 1969
D. A. L. Davies
openalex   +1 more source

Combating cancer immunotherapy resistance: a nano‐medicine perspective

Cancer Communications, EarlyView.
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong, Xintong Xie, Juan Wu, Xiangyu Wang, Wenxiang Zhang, Shuowen Wang, Daria Valerievna Abbasova, Yi Fang, Hongnan Jiang, Jidong Gao, Jing Wang   +10 more
wiley   +1 more source

Identification of potential antigenic peptides of Brucella through proteome and peptidome

Veterinary Medicine and Science, Volume 9, Issue 1, Page 523-534, January 2023., 2023
Based on proteomics and peptidomics, we identified 35 peptides from the Brucella proteome, which have the ability to bind MHC molecules and have the potential to be used in vaccine design. In addition, we also found four Brucella proteins containing the identified MHC‐I and MHC‐II binding peptides, which may be good candidate targets for designing ...
Meijuan Pei, Ao Dong, Xueping Ma, Shulei Li, Yan Guo, Menglan Li, Zhenghui Wang, Hengliang Wang, Li Zhu, Chao Pan, Yufei Wang   +10 more
wiley   +1 more source

HISTOCOMPATIBILITY GENES OF MICE

, 1964
George D. Snell, Helen P. Bunker
openalex   +1 more source

Lipid Metabolism and Immune Function: Chemical Tools for Insights into T‐Cell Biology

ChemBioChem, EarlyView.
This review explores how lipids regulate immune responses, particularly in T‐cell function. Advances in metabolomics and proteomics provide insights into lipid‐mediated immunity. Fluorescent lipids enable single‐cell analysis of lipid uptake and metabolism.
Luuk Reinalda, Mario van der Stelt, Sander Izaak van Kasteren   +2 more
wiley   +1 more source

Missed opportunities to increase efficiency of monoclonal antibody development using hybridoma technology and mice as the source animal

Frontiers in Immunology
Esha Chakravarty, Mehmet T. Dorak
doaj   +1 more source

Etiology of nephrotic syndrome: insights from univariate and multivariate Mendelian randomization study. [PDF]

Ren Fail
Chan H, Yin H, Yang X, Zhang G, Wang M, Yang H, Li Q.   +6 more
europepmc   +1 more source

EVIDENCE FOR A MUTATIONAL EVENT AT THE B BLOOD GROUP-HISTOCOMPATIBILITY LOCUS IN CHICKENS

, 1969
Louis W. Schierman, Raymond A. McBride
openalex   +1 more source