Results 191 to 200 of about 335,757 (388)

Host Cell Protein Clinical Safety Risk Assessment—An Updated Industry Review

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Host cell proteins (HCP) are process‐related impurities that can co‐purify with therapeutic proteins. Some HCP impurities potentially can have an impact on patient safety (immunogenicity or toxicity), efficacy, and/or product quality. It is important to reduce the levels of HCP impurities with a well‐controlled manufacturing process and to ...
Lisette Coye   +19 more
wiley   +1 more source

Major Histocompatibility Complex Class II Deficiency Beyond Infancy. [PDF]

open access: yesCase Reports Immunol
Kattra AB   +7 more
europepmc   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

open access: yesBMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang   +7 more
wiley   +1 more source

PB1833: FUNCTIONAL POLYMORPHISMS OF TLR2-4 & C2 DO NOT PLAY A CRUCIAL ROLE IN INCIDENCE OF INFECTIONS IN A GREEK COHORT OF PATIENTS WITH ACUTE MYELOID LEUKEMIA.

open access: yesHemaSphere, 2022
C. Papadopoulos   +5 more
doaj   +1 more source

The MR1/MAIT cell axis impacts the gut-brain axis through both cognition and microbial community structure in 5XFAD mice. [PDF]

open access: yesAlzheimers Dement
Wyatt-Johnson SK   +6 more
europepmc   +1 more source

Evolutionary aspects of allorecognition [PDF]

open access: yes, 2015
Ballarin, Loriano   +3 more
core  

Home - About - Disclaimer - Privacy