Major histocompatibility complex II serves as a prognostic biomarker in resectable pulmonary sarcomatoid carcinoma: development of a prediction model. [PDF]
Wang H +16 more
europepmc +1 more source
Photo‐responsive carbon dots for pyroptosis‐mediated anti‐tumor application
Photo‐responsive CDs generate ROS to induce tumor cell pyroptosis, thereby stimulating antitumor immunity. Abstract Pyroptosis refers to a kind of lytic programmed cell death, characterized by the release of pro‐inflammatory cytokines during the process. Owing to its immune response stimulation ability, pyroptosis has garnered considerable attention in
Lingyun Li +5 more
wiley +1 more source
Identification of the Novel HLA-DRB1*11:01:49 Allele Using Next-Generation Sequencing in a Chinese Individual. [PDF]
Chen N, Li Q, Dong L, Zhang W, Zhu F.
europepmc +1 more source
This review highlights how chitosan derivatives enhance nanoparticle‐based vaccines through superior stability, mucoadhesion, and immune modulation. By triggering robust mucosal, humoral, and cellular responses, these biocompatible polymers serve as a transformative platform for next‐generation immunotherapeutics and safe and effective vaccine delivery
Sayantani Dasgupta +8 more
wiley +1 more source
Identification of the Novel HLA-C*06:02:01:117 Allele in an Individual From Bihar, India. [PDF]
Karale B, Tambe M, Rajak J, D'Silva SZ.
europepmc +1 more source
Progress in bone tissue engineering biomaterials: Development, challenges, and prospects
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang +7 more
wiley +1 more source
Major Histocompatibility Complex Genomic Regions as Candidates for Reproductive Success in Cattle: From GWAS to Post-GWAS Analysis. [PDF]
Faverzani LB +10 more
europepmc +1 more source
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou +4 more
wiley +1 more source
Evaluation of human leukocyte antigen histocompatibility and its impact on liver transplant graft outcomes. [PDF]
Liu D +8 more
europepmc +1 more source
Genomic Assessment of Reintroduced African Wild Dogs Informs Conservation Translocations
Few reintroduction and translocation programs incorporate genomic assessments into management planning, despite ongoing debate over how founder individuals should be selected. Here, we assess the genomic composition of reintroduced African wild dog (Lycaon pictus) populations in private reserves in South Africa, comparing them with a free‐roaming ...
Michou Weimar +4 more
wiley +1 more source

