Results 231 to 240 of about 193,733 (306)

Identification of Seven Novel HLA Alleles by Third Generation Sequencing. [PDF]

HLA
Sutherland AH, Turner TR, Flaxl LM, Swadling L, Mayor NP.   +4 more
europepmc   +1 more source

From haemostasis to immunity: The expanding frontiers of platelet biology

British Journal of Haematology, EarlyView.
Platelets are versatile cells whose functions extend far beyond haemostasis and thrombosis, actively regulating innate and adaptive immunity, angiogenesis, lymphangiogenesis, liver regeneration, atherosclerosis and tumour metastasis. This demonstrates their central role in various physiological processes and multiple life‐threatening diseases ...
Xun Grace Wu, Nicole Tomei, Heyu Ni
wiley   +1 more source

Identification of the Novel HLA-C*03:536:02 Allele in a Chinese Cord Blood Donor. [PDF]

HLA
Dong L, Wang F, Li Q, He Y, Zhu F.
europepmc   +1 more source

Identification of a Novel HLA-B Allele, HLA-B*35:640, Discovered by Next-Generation Sequencing. [PDF]

HLA
Taha N, Wagenknecht D, Winstead J, Robinson M, Lunz J.   +4 more
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

AI-driven precision immunotherapy: emerging trends from AACR 2026. [PDF]

Biomark Res
Chen Y, Chen M, Xi Y, Xia Y, Ma S, Chen B.   +5 more
europepmc   +1 more source

Histocompatibility: An Historical Perspective

Journal of the Royal College of Physicians of London, 1985
openaire   +2 more sources

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

From thresholds to trajectories: a perspective on reframing alloimmune risk for computational modeling in solid organ transplantation. [PDF]

Front Immunol
Das R, Hod-Dvorai R.
europepmc   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source