High-throughput cloning reveals diverse properties of T-cell receptors targeting minor histocompatibility antigens. [PDF]
Ito S +16 more
europepmc +1 more source
Adaptive Immunity in Marsupials
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol +2 more
wiley +1 more source
AlloPipe and Its Web Server Allogenomics: From Genomic Data to Candidate Minor Histocompatibility Antigens. [PDF]
Dhuyser A +6 more
europepmc +1 more source
The effect of parental and maternal-fetal histocompatibility at MHC on sex ratio in offspring.
The secondary sex ratio (male births of total births) variation was investigated as a function of MHC antigens. Previous studies have indicated that at conception male zygotes are more frequent than female ones and abortions of male fetuses prevail.
MARTINETTI M +3 more
core
Paradoxical Alopecia Areata Induced by IL‐17 and IL‐23 Inhibitors: A Systematic Review
This systematic review identifies consistent clinical patterns of alopecia areata associated with IL‐17 and IL‐23 inhibitors, most frequently involving secukinumab and ustekinumab. Disease severity varied widely, and management often required biologic discontinuation or therapeutic switching.
Isabella Kamholtz +2 more
wiley +1 more source
Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation. [PDF]
Cieri N +36 more
europepmc +1 more source
Nail Lichen Planus in Children ‐ Epidemiology, Pathogenesis, Clinical Presentation, and Treatment
ABSTRACT Nail lichen planus (NLP) is a chronic inflammatory disorder that, while rare in children compared to adults, represents a significant cause of pediatric nail dystrophy that requires early recognition to prevent permanent scarring and nail loss.
Francesca Pampaloni, Matilde Iorizzo
wiley +1 more source
ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint damage. Although ferroptosis has been implicated in RA progression, the role of disulfidptosis and its interaction with ferroptosis remains unclear.
Ting‐Ting Wang +10 more
wiley +1 more source
Autosomal Minor Histocompatibility Antigens: How Genetic Variants Create Diversity in Immune Targets. [PDF]
Griffioen M +2 more
europepmc +1 more source
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang +4 more
wiley +1 more source

