Results 1 to 10 of about 193,733 (306)

Development and clinical implementation of a local automated kidney allocation platform integrating virtual crossmatch [PDF]

Frontiers in Immunology
BackgroundHighly sensitized kidney transplant candidates possess preformed anti-human leukocyte antigen (HLA) antibodies that substantially reduce their likelihood of receiving a compatible deceased-donor organ.
Mohammad Awaji, Mohammad Awaji, Saber AlZahrani, Rafah Bamrdouf, Dalal AlAbduladheem, Amani Mohammed, Mariam Alzahrani, Shaima Alkebasi, Bashaer Mohammad Alshallali, Abdullah Saad Alreaan, Sara Mohammed Bosbait, Sumayah Askandarani, Najib Ashoor Musaied, Khalid Beleed Akkari, Mohammed AlQahtani, Abdulnaser Mohammed Alabadi   +15 more
doaj   +2 more sources

Histocompatibility [PDF]

, 2018
Immune-mediated rejection of tissue allografts was first described in 1945 by the British immunologist Peter Medawar, followed by the discovery of the major histocompatibility complex (MHC) carrying the histocompatibility genes by Peter Gorer and George ...
Spierings, Eric, Fleischhauer, Katharina
openaire   +2 more sources

Pretransplant histocompatibility testing algorithm: Laboratory and clinical approach in the Indian context

Indian Journal of Transplantation, 2021
Remarkable advances in histocompatibility testing have immensely improved the safety of transplantation and have decreased the incidence of rejections.
Feroz Aziz, Aseem K Tiwari, Himanshu V Patel, Rajni Chauhan   +3 more
doaj   +1 more source

Transplanting the Elderly: Mandatory Age- and Minimal Histocompatibility Matching

Frontiers in Immunology, 2020
Worldwide over 40% of patients receiving renal replacement therapy (RRT) are aged 65 years or older, a number that is still increasing. Renal transplantation is the preferred RRT, providing substantial survival benefit over those remaining on dialysis ...
Geertje J. Dreyer, Johan W. de Fijter
doaj   +1 more source

Clinical, immunological and ethical aspects of selecting a recipient for cadaver kidney transplantation

Вестник трансплантологии и искусственных органов, 2020
The decision to choose a particular patient for kidney transplantation is made through two consecutive decisions: decision to include the patient on the waiting list and decision to select a patient competitively among several candidates for transplant ...
V. A. Vatazin, A. B. Zulkarnaev, V. A. Stepanov   +2 more
doaj   +1 more source

Biocompatibility of Biomaterials for Nanoencapsulation: Current Approaches

Nanomaterials, 2020
Nanoencapsulation is an approach to circumvent shortcomings such as reduced bioavailability, undesirable side effects, frequent dosing and unpleasant organoleptic properties of conventional drug delivery systems. The process of nanoencapsulation involves
Bwalya A. Witika, Pedzisai A. Makoni, Scott K. Matafwali, Billy Chabalenge, Chiluba Mwila, Aubrey C. Kalungia, Christian I. Nkanga, Alain M. Bapolisi, Roderick B. Walker   +8 more
doaj   +1 more source

Gene duplication and fragmentation in the zebra finch major histocompatibility complex [PDF]

, 2010
BACKGROUND: Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects.
Tina Graves, Griffin, D.K., Wesley C Warren, Edwards, Scott, Völker, Martin, Völker Martin, Westerdahl Helena, Burt, D.W., Graves, Tina, Griffin Darren K, Martin Völker, Burt, David W, Darren K Griffin, Helena Westerdahl, Godinez Ricardo, Edwards, S.V., Edwards, Scott V, Kotkiewicz, H., Ekblom, Robert,, Ekblom Robert, Warren, Wesley C, Warren, W.C., Ekblom, Robert, Robert Ekblom, David W Burt, Ricardo Godinez, Warren, Wesley C., Scott V Edwards, Lund University., Griffin, Darren K., Godinez, Ricardo, Westerdahl, Helena, Ekblom, R., Westerdahl, Helena,, Edwards, Scott V., Kotkiewicz, Holly, Voelker, Martin, Graves Tina, Christopher N Balakrishnan, Balakrishnan, Christopher N, Godinez, R., Warren Wesley C, Burt David W, Balakrishnan, Christopher N., Kotkiewicz Holly, Griffin, Darren K, Westerdahl, H., Balakrishnan Christopher N, Balakrishnan, C.N., Graves, T., Graves, Tina A., Burt, David W., Holly Kotkiewicz, Volker, M., Edwards Scott V   +54 more
core   +1 more source

Hilliard Seigler, M.D. and the origins of kidney transplantation and immunology at Duke

Frontiers in Transplantation, 2023
The contributions of Dr. Hilliard Seigler to the founding of the Duke kidney transplantation program were considerable in both surgery and immunology. Some of these highlights are summarized based upon interviews with Dr. Seigler by the authors.
Stuart J. Knechtle, Justin Barr
doaj   +1 more source

Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility complex class I molecules into the medial-Golgi compartment [PDF]

, 1992
Selective expression of murine cytomegalovirus (MCMV) immediate-early (IE) genes leads to the presentation by the major histocompatibility complex (MHC) class I molecule L a of a peptide derived from MCMV IE protein pp89 (Reddehase, M. J., J.
Koszinowski, Ulrich H., Hartlaub, Udo, T Ruppert, U H Koszinowski, H Hengel, Del Val, Margarita, Lucin, Pero, U Hartlaub, M del Val, P Lucin, Häcker, Hans, Ruppert, Thomas, H Häcker, Hengel, Hartmut   +13 more
core   +1 more source

Qualitative and quantitative comparison of cell-free DNA and cell-free fetal DNA isolation by four (semi-)automated extraction methods: impact in two clinical applications: chimerism quantification and noninvasive prenatal diagnosis

Journal of Translational Medicine, 2021
Background Non-invasive molecular analysis of cell-free DNA (cfDNA) became a sensitive biomarker for monitoring organ transplantation or for detection of fetal DNA (cffDNA) in noninvasive prenatal test. In this study, we compared the efficiencies of four
Pascal Pedini, Hajer Graiet, Laurine Laget, Lugdivine Filosa, Jade Chatron, Nicem Cherouat, Jacques Chiaroni, Lucas Hubert, Coralie Frassati, Christophe Picard   +9 more
doaj   +1 more source