Results 21 to 30 of about 193,733 (306)

Highly Sensitized Patients Are Well Served by Receiving a Compatible Organ Offer Based on Acceptable Mismatches

Frontiers in Immunology, 2021
Highly sensitized kidney patients accrue on the transplant waiting list due to their broad immunization against non-self Human Leucocyte Antigens (HLA).
Sebastiaan Heidt, Geert W. Haasnoot, Marissa J. H. van der Linden-van Oevelen, Frans H. J. Claas   +3 more
doaj   +1 more source

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by D94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis [PDF]

, 1998
Human histocompatibility leukocyte antigen (HLA)-E is a nonclassical HLA class I molecule, the gene for which is transcribed in most tissues. It has recently been reported that this molecule binds peptides derived from the signal sequence of HLA class I ...
John E. Coligan, Matthias Ulbrecht, Ulbrecht, Matthias, Coligan, John E., Andrew G. Brooks, Brooks, AG, Borrego, F, Coligan, JE, Elisabeth H. Weiss, Brooks, Andrew G., Francisco Borrego, Borrego, Francisco, Weiss, Elisabeth H., Ulbrecht, M, Weiss, EH   +14 more
core   +1 more source

Biocompatibility of polyetheretherketone for the treatment of orbital bone defects [PDF]

International Journal of Ophthalmology, 2020
AIM: To investigate the biocompatibility and therapeutic effects of polyetheretherketone (PEEK) on recovery of a rabbit orbital defect. METHODS: Totally 16 New Zealand rabbits were used to establish an orbital bone defect model and then randomly divided
Rui-Dong Gu, Fan Xiao, Lin Wang, Kai-Jian Sun, Lin-Lin Chen   +4 more
doaj   +1 more source

Immunological basis of differences in disease resistance in the chicken [PDF]

, 2002
Genetic resistance to diseases is a multigenic trait governed mainly by the immune system and its interactions with many physiologic and environmental factors.
Rebel, J.M.J., Zekarias, B., Huurne, A.A.H.M., ter, Landman, W.J.M., Gruys, E., Pol, J.M.A.   +5 more
core   +1 more source

Accuracy of Programs for the Determination of Human Leukocyte Antigen Alleles from Next-Generation Sequencing Data

Frontiers in Immunology, 2017
The human leukocyte antigen (HLA) genes code for proteins that play a central role in the function of the immune system by presenting peptide antigens to T cells.
Antti Larjo, Robert Eveleigh, Elina Kilpeläinen, Tony Kwan, Tomi Pastinen, Satu Koskela, Jukka Partanen   +6 more
doaj   +1 more source

A Physical Map Including a New Class I Gene (cda12) of the Human Major Histocompatibility Complex (A2/313 Haplotype) Derived from a Monosomy 6 Mutant Cell Line [PDF]

, 1989
To avoid interpretative problems due to restriction fragment length polymorphisms, the monosomy 6 mutant cell line BM19.7 was employed to establish a molecular map of the human major histocompatibility (HLA) complex in the A2,B13,Bw4,DRw6,DRw52,DQw1,DPw2
Pohla, Heike, Bloemer, K, Messer, Gerald, Bloemer, Katharina, Messer, G, Ziegler, Andreas, Ragoussis, Jiannis, Ragoussis, J, Weiss, Elisabeth H., Pohla, H, Weiss, EH, Ziegler, A   +11 more
core   +1 more source

The Accuracy of Sequence-Specific Oligonucleotide and Real-Time Polymerase Chain Reaction HLA Typing in Determining the Presence of Pre-Transplant Donor-Specific Anti-HLA Antibodies and Total Eplet Mismatches for Deceased Donor Kidney Transplantation

Frontiers in Immunology, 2022
High resolution human leukocyte antigen (HLA) typing is important in establishing eplet compatibility and the specificity of donor-specific anti-HLA antibodies (DSA).
Nicholas G. Larkins, Nicholas G. Larkins, Lloyd D’Orsogna, Anne Taverniti, Ankit Sharma, Ankit Sharma, Ankit Sharma, Aron Chakera, Doris Chan, Anoushka Krishnan, Germaine Wong, Germaine Wong, Germaine Wong, Wai H. Lim, Wai H. Lim   +14 more
doaj   +1 more source

Female rose bitterling prefer MHC-dissimilar males : experimental evidence [PDF]

, 2012
The role of genetic benefits in female mate choice remains a controversial aspect of sexual selection theory. In contrast to “good allele” models of sexual selection, “compatible allele” models of mate choice predict that females prefer mates with ...
Bryja, Pepa, Bryjova, Anna, Josef Bryja (150556), Smith, Carl, Spence, Rowena Grace Alison, Martin Reichard (150549), Martin Reichard, Rowena Spence, Rowena Spence (150551), Carl Smith, Anna Bryjová, Josef Bryja, Anna Bryjová (150553), Martin Reichard, Reichard, Martin, Carl Smith (150560)   +15 more
core   +2 more sources

Transfusion-associated graft-versus-host disease (TA-GVHD) and graft-versus-host disease (GVHD): Pathophysiology and management (contrasted and compared)

Hematology/Oncology and Stem Cell Therapy
Transfusion of blood products is a common lifesaving medical procedure in clinical practice. However, it poses the risk of potential adverse reactions for the recipient.
Serena Valsami, Georgios Dryllis, Kassiani Papanastasi, Styliani Kokoris, Anastasios Kriebardis, Konstantinos Nikitiadis, Konstantinos Konstantopoulos, Marianna Politou   +7 more
doaj   +1 more source

Histocompatibility

AbstractHuman leukocyte antigen (HLA) molecules are the most important histocompatibility antigens, due to their genetic polymorphism and their key role in peptide antigen presentation and T-cell alloreactivity. While full matching for the most relevant HLA loci had been regarded as a prerequisite for successful transplantation until recently, the ...
Spierings, Eric, Madrigal, Alejandro, Fleischhauer, Katharina   +2 more
  +6 more sources