T-lymphocyte response to cytochrome c. I. Demonstration of a T-cell heteroclitic proliferative response and identification of a topographic antigenic determinant on pigeon cytochrome c whose immune recognition requires two complementing major histocompatibility complex-linked immune response genes. [PDF]
A M Solinger+3 more
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The contribution of extracellular RNA and its derived biomaterials in disease management
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei+8 more
wiley +1 more source
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang+11 more
wiley +1 more source
Combating cancer immunotherapy resistance: a nano‐medicine perspective
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong+10 more
wiley +1 more source
A New Histogenetic Method for Minor Histocompatibility Antigen Typing [PDF]
Věra Hauptfeld, Jan Klein
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Contemporary Perspectives on Chronic Renal Disorders
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok+5 more
wiley +1 more source
Matching of histocompatibility (HL-A) antigens for platelet transfusion [PDF]
Mittal Kk, E. A. Ruder, D Green
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Streptococcal M Protein Vaccines, Rheumatic Fever and Human Histocompatibility Antigens [PDF]
Eugene N. Fox, Raymond D. A. Peterson
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Identification of Natural Killer Cell Enhancers Through Mimicking of the Tumor Microenvironment
The ability of natural killer (NK) cells to identify and eliminate cancer cells is reduced within the tumor microenvironment (TME), allowing cancer to evade detection and eradication by immune cells. We developed a novel co‐culture assay that replicates the immunosuppressive TME conditions to facilitate the discovery of compounds that can prevent NK ...
Aylin Binici+11 more
wiley +1 more source