Results 301 to 310 of about 150,657 (357)

Vaccine-induced donor-specific HLA antibodies: a case report highlighting sensitization risks in renal transplant waitlisted patients. [PDF]

Front Immunol
Kakodkar P, Shekari N, Mainra R, Webster D, Pearce T, Wu F, Mostafa A.   +6 more
europepmc   +1 more source

Revolutionising Cancer Immunotherapy: Advancements and Prospects in Non‐Viral CAR‐NK Cell Engineering

Cell Proliferation, Volume 58, Issue 4, April 2025.
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou, Yifeng Chen, Yuhao Ba, Hui Xu, Anning Zuo, Shutong Liu, Yuyuan Zhang, Siyuan Weng, Yuqing Ren, Peng Luo, Quan Cheng, Lulu Zuo, Shanshan Zhu, Xing Zhou, Chuhan Zhang, Yukang Chen, Xinwei Han, Teng Pan, Zaoqu Liu   +18 more
wiley   +1 more source

Canine intestinal organoids as a platform for studying MHC class II expression in epithelial cells. [PDF]

BMC Mol Cell Biol
Nakazawa M, Nagao I, Ambrosini YM.
europepmc   +1 more source

Genetically Engineered Hypoimmune Human Muscle Progenitor Cells Can Reduce Immune Rejection

Cell Proliferation, Volume 58, Issue 4, April 2025.
Cells face two challenges after transplantation: recognition and killing by lymphocytes, and cell apoptosis induced by the transplantation environment. Our hypoimmune cells aim to address these two challenges through editing of immunomodulatory proteins and overexpression of anti‐apoptotic proteins.
Yu Chen, Peng Wang, Shilin Ma, Chenran Yue, Xupeng Liu, Yeqian Cheng, Kun Liu, Tongbiao Zhao, Ng Shyh‐Chang   +8 more
wiley   +1 more source

Editorial: Novel applications of epitope biology to improve outcomes in transplantation. [PDF]

Front Genet
Lan JH, Liwski R, Lima ACM, Tafulo S.
europepmc   +1 more source

PD‐L1 Promotes Immunological Tolerance and Enhances Visual Protection of hESC‐RPE Grafts in Retinal Degeneration

Cell Proliferation, EarlyView.
We generated immune‐tolerant mature hESC‐RPE cells by overexpressing PD‐L1. PD‐L1‐expressing hESC‐RPE grafts exhibited significantly higher survival, reduced apoptosis and enhanced visual protection in retinal degeneration models, which presents an alternative target to improve the efficiency of hESC‐RPE‐based therapy for AMD. ABSTRACT Immune rejection
Bowen Li, Xue Zhang, Yajie Fang, Min Chen, Qiyou Li, Yuxiao Zeng, Chunge Ren, Chengang Wang, Yingxue Lv, Jia Lu, Hongling Liu, Yong Liu   +11 more
wiley   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Editorial: Community series in the role of CD1- and MR1-restricted T cells in immunity and disease, volume II. [PDF]

Front Immunol
Iwabuchi K, Van Kaer L.
europepmc   +1 more source

Genetic Polymorphisms in MHC Classes I and II Predict Outcomes in Metastatic Colorectal Cancer. [PDF]

Int J Mol Sci
Mittal P, Battaglin F, Yang Y, Soni S, Stintzing S, Parikh AR, Ashouri K, Algaze S, Jayachandran P, Torres-Gonzalez L, Zhang W, Cremolini C, Heinemann V, Millstein J, Singh IK, Lenz HJ.   +15 more
europepmc   +1 more source