Antigen processing and presentation in cancer immunotherapy
Background Knowledge about and identification of T cell tumor antigens may inform the development of T cell receptor-engineered adoptive cell transfer or personalized cancer vaccine immunotherapy.
Maxwell Y Lee +3 more
doaj +1 more source
Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules. [PDF]
Ly49 receptor genes are expressed by subsets of natural killer (NK) cells in an overlapping fashion, accounting for the capacity of NK subsets to attack host cells that have selectively downregulated self-major histocompatibility complex (MHC) class I ...
Hanke, T +4 more
core +1 more source
Common Genetic Variant Association with Altered HLA Expression, Synergy with Pyrethroid Exposure, and Risk for Parkinson's Disease: An Observational and Case-Control Study. [PDF]
Background/objectivesThe common non-coding single nucleotide polymorphism (SNP) rs3129882 in HLA-DRA is associated with risk for idiopathic Parkinson's disease (PD).
Boss, JM +11 more
core +2 more sources
Association between canine leishmaniosis and Ehrlichia canis co-infection: a prospective case-control study [PDF]
Background In the Mediterranean basin, Leishmania infantum is a major cause of disease in dogs, which are frequently co-infected with other vector-borne pathogens (VBP).
A Mazeris +55 more
core +5 more sources
Differences in clinicopathologic variables between Borrelia C6 antigen seroreactive and Borrelia C6 seronegative glomerulopathy in dogs. [PDF]
BackgroundRapidly progressive glomerulonephritis has been described in dogs that seroreact to Borrelia burgdorferi, but no studies have compared clinicopathologic differences in Lyme-seroreactive dogs with protein-losing nephropathy (PLN) versus dogs ...
Goldstein RE +6 more
core +1 more source
Improvements in the preparation of heterologous antilymphocyte globulin with special reference to absorption and diethylaminoethyl cellulose batch production [PDF]
Antilymphocyte gamma-G globulin (ALGG) was produced from the serum of immunized horses. Modifications of the preliminary absorption techniques permitted the removal of undesirable, extraneous antibodies.
Amend, JR +5 more
core
The Major Histocompatibility Complex and Perfumers' Descriptions of Human Body Odors
The MHC (major histocompatibility complex) is a group of genes that play a crucial role in immune recognition and in tolerance of tissue grafting. The MHC has also been found to influence body odors, body odor preferences, and mate choice in mice and ...
Claus Wedekind +3 more
doaj +1 more source
Hematopoietic stem cell transplantation is the treatment of choice for many hematologic diseases, such as multiple myeloma, bone marrow aplasia and leukemia.
Danilo Santana Alessio Franceschi +5 more
doaj +1 more source
Immunity to MHC class I antigen after direct DNA transfer into skeletal muscle. [PDF]
Plasmid cDNA encoding the alpha-chain of either membrane-bound (pcRT.45) or secreted (pcRQ.B3) RT1Aa MHC class I Ag were transferred to Lewis (RT1(1)) rat skeletal muscle by direct injection.
Burlingham, William J. +4 more
core
Assessing the utilization of high-resolution 2-field HLA typing in solid organ transplantation. [PDF]
HLA typing in solid organ transplantation (SOT) is necessary for determining HLA-matching status between donor-recipient pairs and assessing patients\u27 anti-HLA antibody profiles.
Dinh, Anh +16 more
core +1 more source

