Results 91 to 100 of about 399,979 (311)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Steganalytic Methods for the Detection of Histogram Shifting Data Hiding Schemes

, 2012
Peer-reviewedIn this paper, several steganalytic techniques designed to detect the existence of hidden messages using histogram shifting schemes are presented.
Lerch Hostalot, Daniel, Megías Jiménez, David   +1 more
core  

PENGARUH PENGGUNAAN MODUL MATEMATIKA TERHADAP MINAT DAN PRESTASI BELAJAR SMK PGRI 2 KEDIRI

, 2022
Penelitian bertujuan melihat pengaruh penggunaan modul pembelajaran terhadap minat dan prestasi belajar matematika pada siswa kelas X AKL SMK PGRI 2 Kediri. Jenis penelitian kuantitatif, desain penelitian eksperimen semu dengan jenis Pretest – Posttest
Yohanie, Dian Devita, Bayu, Cindivia Putri, Handayani, Aprilia Dwi   +2 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Bilateral Histogram Equalization for Contrast Enhancement

, 2016
As image enhancement is a well discussed issue, various methods have already been proposed till to date. Some of these methods perform well for specific applications but most of the techniques suffer from artifacts due to the over or under enhancement ...
Dey, Emon Kumar, Amil, Feroz Mahmud, Rahman, Shanto, Rahman, Md Mostafijur   +3 more
core   +1 more source

Identification of the Structure of Liquid–Gas Flow in a Horizontal Pipeline Using the Gamma-Ray Absorption and a Convolutional Neural Network

Applied Sciences
Knowledge of the liquid–gas flow regime is important for the proper control of many industrial processes (e.g., in the mining, nuclear, petrochemical, and environmental industries).
Robert Hanus, Marcin Zych, Piotr Ochał, Małgorzata Augustyn   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Multiscale Gradient Maps Augmented Fisher Information-Based Image Edge Detection

IEEE Access, 2020
Image edge detection is an important task in image processing and pattern recognition. Edges in digital images signify image discontinuities and traditionally gradient information is utilized in finding possible edge pixels.
V. B. Surya Prasath, Dang Ngoc Hoang Thanh, Nguyen Quoc Hung, Le Minh Hieu   +3 more
doaj   +1 more source