Results 71 to 80 of about 423,557 (264)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

DEVELOPMENT OF STUDENT WORKSHEET BASED ON CONTEXTUAL TEACHING AND LEARNING [PDF]

open access: yes, 2023
The students had difficulty in understanding comparative material in mathematics subject, especially its application in everyday life. In addition, there was no Contextual Teaching and Learning-Based Student Worksheet (LKPD) on comparative material. This
Sari, Citra Permata   +3 more
core   +1 more source

SUPERVISED AUTOMATIC HISTOGRAM CLUSTERING AND WATERSHED SEGMENTATION. APPLICATION TO MICROSCOPIC MEDICAL COLOR IMAGES

open access: yesImage Analysis and Stereology, 2011
In this paper, an approach to the segmentation of microscopic color images is addressed, and applied to medical images. The approach combines a clustering method and a region growing method.
Olivier Lezoray
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A New Fast Histogram Matching Algorithm for Laser Scan Data

open access: yes, 2008
This paper presents a new fast histogram matching algorithm for tracking the position and orientation of robots without the help of any odometers. Histogram avoids extracting geometrical primitives from the sensor data, acts independently from odometers,
Quan Qiu   +3 more
core   +1 more source

Histogram affine invariants extraction method based on two-scale auto-convolution

open access: yesTongxin xuebao, 2012
A two-scale auto-convolution histogram affine invariant was proposed.A two-scale auto-convolution transformation was established based on the new image generated by two-dimensional linear transform of image coordinates.Then the value of the new image ...
Bo HUANG   +4 more
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

DMR50 – the first digital terrain model of Slovakia in the GCCA SR sector [PDF]

open access: yesActa Montanistica Slovaca, 2005
The digital terrain model (DTM) is a complex object of the Primary Database for The Geographic Information System (PD GIS). PD GIS is a component of the Automated Information System of Geodesy, Cartography and Cadastre.
Matej Klobušiak, Miloslav Ofúkaný
doaj  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

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