Results 71 to 80 of about 399,979 (311)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
fast-histogram v0.7: fast simple 1D and 2D histograms in Python
, 2019 Sometimes you just want to compute simple 1D or 2D histograms with regular bins. Fast. No nonsense. Numpy’s histogram functions are versatile, and can handle for example non-regular binning, but this versatility comes at the expense of performance.
Robitaille, Thomas P +1 more
core +1 more source
VALIDITAS LKPD DIGITAL INTERAKTIF DENGAN AUGMENTED REALITY PADA MATERI VEKTOR DIMENSI 3 [PDF]
, 2023 Evolusi teknologi yang terjadi selama beberapa dekade ini memiliki dampak yang cukup signifikan dalam dunia pendidikan khususnya dalam mengembangkan bahan ajar seperti Lembar Kerja Peserta Didik (LKPD).
Tsabitah, Irbah, Sunismi, Sunismi
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Two improved forensic methods of detecting contrast enhancement in digital images [PDF]
, 2014 Contrast enhancements, such as histogram equalization or gamma correction, are widely used by malicious attackers to conceal the cut-and-paste trails in doctored images.
Xufeng Lin +5 more
core +1 more source
Pembelajaran Matematika Berbasis Teknologi dalam Perspektif Filsafat Matematika [PDF]
, 2022 Sebagai ilmu tentang pencarian kebenaran berdasarkan nalar, filsafat memiliki kontribusi besar dalam perkembangan matematika dan teknologi, termasuk dalam pembelajaran matematika berbasis teknologi yang tidak terpisahkan satu sama lain. Â Cabang filsafat,
Shobrun, Yunus, Dewi, Izwita
core +1 more source
Semi-Automated Surface Water Detection with Synthetic Aperture Radar Data: A Wetland Case Study
Remote Sensing, 2017 In this study, a new method is proposed for semi-automated surface water detection using synthetic aperture radar data via a combination of radiometric thresholding and image segmentation based on the simple linear iterative clustering superpixel ...
Amir Behnamian +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
PENGEMBANGAN MEDIA PEMBELAJARAN MACROMEDIA FLASH MATERI SEGITIGA PADA SISWA SMP KELAS VII [PDF]
, 2021 Penelitian ini bertujuan untuk mengetahui proses pengembangan media pembelajaran Macromedia Flash materi segitiga, dengan menghasilkan media pembelajaran Macromedia Flash yang valid, praktis dan efektif materi segitiga pada siswa SMP kelas VII.
Mamoh, Oktovianus +2 more
core +1 more source