Results 41 to 50 of about 18,673 (292)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Steganalytic methods for the detection of histogram shifting data-hiding schemes [PDF]

, 2011
In this paper, some steganalytic techniques designed to detect the existence of hidden messages using histogram shifting methods are presented. Firstly, some techniques to identify specific methods of histogram shifting, based on visible marks on the ...
Lerch Hostalot, Daniel
core  

Lossless Data Hiding Using Histogram Shifting Method Based on Integer Wavelets [PDF]

, 2006
This paper1 proposes a histogram shifting method for image lossless data hiding in integer wavelet transform domain. This algorithm hides data into wavelet coefficients of high frequency subbands.
Yao, Qiuming, Guorong Xuan, Ni, Zhicheng, Xuan, Guorong, Chai, Peiqi, Yun Q. Shi, Qiuming Yao, Chengyun Yang, Shi, Yun Q., Jianjiong Gao, Yang, Chengyun, Zhicheng Ni, Gao, Jianjiong, Peiqi Chai   +13 more
core   +1 more source

A Subsampling and Interpolation Technique for Reversible Histogram Shift Data Hiding [PDF]

, 2010
This paper proposes a novel reversible data hiding algorithm for images, which the original host image can be exactly recovered from the marked image after the hidden data has been extracted. The proposed algorithm considers shifting the histogram of the difference values between the subsampled target pixel intensities and their interpolated ...
Yih-Chuan Lin, Tzung-Shian Li, Yao-Tang Chang, Chuen-Ching Wang, Wen-Tzu Chen   +4 more
openaire   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Modifikasi Metode Histogram Shifting dan Neighbouring Similarity untuk Steganografi pada Video Digital [PDF]

, 2018
Steganography merupakan salah satu metode yang digunakan untuk menyembunyikan informasi. Dengan steganography, informasi akan disembunyikan dengan cara menyisipkan informasi tersebut kedalam data lain. Contoh dari steganography adalah histogram shifting
Fatman, Alek Nur
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

A Reversible Data Hiding Method by Histogram Shifting in High Quality Medical Images [PDF]

, 2013
[[abstract]]Enormous demands for recognizing complicated anatomical structures in medical images have been demanded on high quality of medical image such as each pixel expressed by 16-bit depth.
Huan, Li-Chin;Huang, Li-Chin;Tseng, Lin-Yu;Tseng, Lin-Yu;黃明祥;Hwang, Min-Shiang
core  

Sand-Dust Image Enhancement Using Successive Color Balance With Coincident Chromatic Histogram

IEEE Access, 2021
Outdoor images in sand-dust environments play an adverse role in various remote-based computer vision tasks because captured sand-dust images have severe color casts, low contrast, and poor visibility.
Tae Hee Park, Il Kyu Eom
doaj   +1 more source