Results 81 to 90 of about 10,736,177 (356)

Evaluation of the risk malignancy index diagnostic value in patients with adnexal masses [PDF]

Vojnosanitetski Pregled, 2011
Background/Aim. Ovarian cancer is the leading cause of death from gynecologic malignancies. Risk of malignancy index (RMI) is recommended in assessment of patients with adnexal masses.
Terzić Milan, Dotlić Jelena, Likić-Lađević Ivana, Atanacković Jasmina, Lađević Nebojša   +4 more
doaj   +1 more source

A comparative study of two histological techniques for the identification of cytomegalovirus infection in colorectal biopsies from patients with chronic inflammatory bowel disease.

Revista Espanola de Enfermedades Digestivas, 2009
BACKGROUND the role that cytomegalovirus (CMV) plays in inflammatory bowel disease (IBD) is controversial. The diagnosis of CMV infection in IBD depends on viral identification with hematoxylin-eosin (HE) or immunohistochemistry (IHC).
M. D. de Castro, A. Tardío, V. del Campo, A. Estévez, J. Pineda, F. Domínguez, J. A. Hermo, J. Clofent   +7 more
semanticscholar   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Some considerations on the WHO Histological classification of laryngeal neoplasms [PDF]

, 2019
A new edition of the World Health Organization (WHO) Histological classification of tumours of the hypopharynx, larynx, trachea and parapharyngeal space was published in 2017.
Devaney, Kenneth O., Ferlito, Alfio, Hellquist, Henrik, Hunt, Jennifer L.   +3 more
core   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Ecotoxicological consequences of heavy metals on emperor fish (lethrinus) species in the red sea: histopathology and biochemistry [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
Heavy metal (HMs) contamination in marine environments is a global concern, affecting fish health and seafood safety. This study examined the effects of HMs on 90 emperor fish from the Red Sea, focusing on metal levels in water and fish liver, blood ...
Soha A. ALSOLMY, Raoum MOMINKHAN, Sahar J. MELEBARY   +2 more
doaj   +1 more source

Gonad development and reproduction in the monoecious species Chlorophthalmus agassizi (Actinopterygii: Aulopiformes: Chlorophthalmidae) from the Sardinian Waters (Central-Western Mediterranean) [PDF]

, 2010
Background. The shortnose greeneye, Chlorophthalmus agassizi Bonaparte, 1840, is a species with a circumglobal distribution and is among the most abundant commercial fishes in some Mediterranean areas.
Cabiddu S, Cau A, Follesa MC, Porcu C
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

The determination of specificity, sensitivity and accuracy of core needle biopsy in the diagnosis of parotid and submandibular salivary glands tumors [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. The diagnosis of tumors of salivary glands relies heavily on radiological examination and biopsy of pathological tissue. The aim of this study was to investigate the sensitivity, specificity and accuracy of core needle biopsy in diagnosis
Oroz Aleksandar, Bokun Zorana, Antonijević Đorđe, Jevđić Jasna   +3 more
doaj   +1 more source

A case report of a rare intramuscular granular cell tumor [PDF]

, 2015
Background: Granular cell tumors (GCTs) were firstly described by Weber in 1854 and 70 years later by Abrikossoff and classified as benign tumors. Originally considered muscle tumors, they have been identified as neural lesions, due to their close ...
Cacciotti, Jessica, Cirenza, Mirko, DELLA ROCCA, Carlo, Labate, Agata, Laghi, Andrea, Lo Schiavo, Maria Grazia, Mazzitelli, Riccardo, Petrozza, Vincenzo, Porta, Natale   +8 more
core   +1 more source