Results 91 to 100 of about 166,900 (293)
Rangifer, 1990 The histological structure and secretory function of the common bile duct (ductus hepaticus communis) has not been previously described in reindeer. Macroscopical studies were thus performed in 25 reindeer to reveal the morphology and topography of the ...
Timo Rahko, Sven Nikander
doaj +1 more source
Molecular Oncology, EarlyView.The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh +6 more
wiley +1 more source
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source
Histological Changes in the Lung and Liver Tissues in Mice Exposed to Pyrethroid Inhalation
Walailak Journal of Science and Technology, 2013 Cypermethrin, a type II pyrethroid, is one of the most widely used insecticides in Pakistan. It is considered to be a safe pesticide; however, the possible health hazards of this pyrethroid have been ignored.
Nadeem SHEIKH +5 more
doaj +1 more source
Using Ensemble Models in the Histological Examination of Tissue Abnormalities [PDF]
arXiv, 2015 Classification models for the automatic detection of abnormalities on histological samples do exists, with an active debate on the cost associated with false negative diagnosis (underdiagnosis) and false positive diagnosis (overdiagnosis). Current models tend to underdiagnose, failing to recognize a potentially fatal disease.
arxiv
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Assessment of Breast Cancer Histology using Densely Connected Convolutional Networks [PDF]
arXiv, 2018 Breast cancer is the most frequently diagnosed cancer and leading cause of cancer-related death among females worldwide. In this article, we investigate the applicability of densely connected convolutional neural networks to the problems of histology image classification and whole slide image segmentation in the area of computer-aided diagnoses for ...
arxiv
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Histological images segmentation of mucous glands [PDF]
arXiv, 2018 Mucous glands lesions analysis and assessing of malignant potential of colon polyps are very important tasks of surgical pathology. However, differential diagnosis of colon polyps often seems impossible by classical methods and it is necessary to involve computer methods capable of assessing minimal differences to extend the capabilities of the ...
arxiv