Results 81 to 90 of about 2,155,308 (355)
Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The evolving understanding of histology as an endpoint in ulcerative colitis [PDF]
Intestinal ResearchA therapeutic goal for patients with ulcerative colitis (UC) is deep remission including clinical remission and mucosal healing. Mucosal healing was previously defined by endoscopic appearance, but recent studies demonstrate that histological ...
Shintaro Akiyama +2 more
doaj +1 more source
Multi-class texture analysis in colorectal cancer histology
Scientific Reports, 2016 Automatic recognition of different tissue types in histological images is an essential part in the digital pathology toolbox. Texture analysis is commonly used to address this problem; mainly in the context of estimating the tumour/stroma ratio on ...
Jakob Nikolas Kather +7 more
semanticscholar +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Treatment of low-grade gastric malt lymphoma using Helicobacter pylori eradication [PDF]
Vojnosanitetski Pregled, 2015 Background/Aim. Lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) of the stomach usually occurs as a consequence of Helicobacter pylori (H. pylori) infection. The aim of this study was to investigate the long-term effect of treatment
Grgov Saša +5 more
doaj +1 more source
CMV in the gut: a critical review of CMV detection in the immunocompetent host with colitis. [PDF]
, 2015 As scientific techniques for the detection of cytomegalovirus (CMV) improve, we are able to detect small amounts of CMV in the mucosal wall. As clinicians, we are unsure how to interpret the results of this novel test.
Goodman, AL +4 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Impact of dental implant insertion method on the periimplant epithelial seal: Experimental study on dogs [PDF]
Vojnosanitetski Pregled, 2010 Background/Aim. There is a controversial opinion among implantologists on the method of dental implantation that provides more favourable response of soft and bone tissues.
Matić Smiljana +6 more
doaj +1 more source
Classification of Breast Cancer Based on Histology Images Using Convolutional Neural Networks
IEEE Access, 2018 In recent years, the classification of breast cancer has been the topic of interest in the field of Healthcare informatics, because it is the second main cause of cancer-related deaths in women. Breast cancer can be identified using a biopsy where tissue
Dalal Bardou +2 more
semanticscholar +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source