Results 91 to 100 of about 1,001,459 (297)

Bioresorbable Film for the Prevention of Adhesion to the Anterior Spine After Anterolateral Discectomy [PDF]

, 2009
Background context The development of scar tissue and adhesions postoperatively is a natural consequence of healing but can be associated with medical complications and render reoperation difficult.
Klopp, Lisa S., Rao, Sangeeta, Tai, Joseph W., Thomas, Kevin A., Toth, Jeffrey M., Turner, Simon, Welch, William C.   +6 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

TRIM21 as a Context-Dependent Regulator in Hepatocellular Carcinoma: Integrating Etiological Landscapes (HBV/NASH) with Core Tumor Progression Mechanisms

Journal of Hepatocellular Carcinoma
Jiatong Sun,1 Zixuan Gao,2 Yuanhao Li,3 Jiajun Gao,1 Peiyin Wang,1 Yibo Qin,1 Yanru Chen,4 Ruihong Zhang1 1Key Laboratory for Experimental Teratology of Ministry of Education, Department of Histology and Embryology, School of Basic Medical Sciences ...
Sun J, Gao Z, Li Y, Gao J, Wang P, Qin Y, Chen Y, Zhang R   +7 more
doaj  

Plasma cell myeloma in a 9‐year‐old male: Case report and literature review

Clinical Case Reports
Key Clinical Message Plasma cell myeloma is a rare entity in the pediatric population. The peak incidence is in the seventh decade, with less than 2% of cases occurring in patients under the age of 40.
Kato Ronald, Ambaru Jacinta, Ssebagala Umaru   +2 more
doaj   +1 more source

The etiology and differential diagnosis of “autoimmune hepatitis-like liver disease” in children: a single-center retrospective study

Frontiers in Pediatrics
BackgroundChildren with autoimmune hepatitis (AIH) often present with symptoms similar to those of other liver diseases. This study consists of a comparison between the clinical and histological characteristics of AIH and those of other four AIH-like ...
Di Ma, Xinglou Liu, Guo Ai, Wen Pan, Lingling Liu, Yuan Huang, Yi Liao, Yuanyuan Lu, Zhan Zhang, Hua Zhou, Zhihua Huang, Xingjie Hao, Sainan Shu, Feng Fang   +13 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Exosomes Derived From Human Mesenchymal Stem Cells Mitigate Follicular Interstitial Cell Ferroptosis via the miR-26a-5p/PTEN/GPX4 Axis in Rats with Chemotherapy-Induced Premature Ovarian Insufficiency

International Journal of Nanomedicine
Juntong Chen,1,* Xingyu Huo,1,* Maojiao Qian,1 Qian Xue,1 Yu He,1 Pengzhan Xu,1 Yueming Wang,1 Xiaoxuan Tang,1 Qianqian Luo,1 Hongchu Bao,2,3 Yanlian Xiong1 1Xu Rongxiang Regenerative Medicine Research Center, Binzhou Medical University ...
Chen J, Huo X, Qian M, Xue Q, He Y, Xu P, Wang Y, Tang X, Luo Q, Bao H, Xiong Y   +10 more
doaj  

Intra-operative point-of-procedure delineation of oral cancer margins using optical coherence tomography. [PDF]

, 2019
ObjectivesSurgical margin status is a significant determinant of treatment outcome in oral cancer. Negative surgical margins can decrease the loco-regional recurrence by five-fold.
Agarwal, Sagar, Chen, Zhongping, Hedne, Naveen, Heidari, Emon, James, Bonney Lee, Kuriakose, Moni Abraham, Muralidharan, Anjana, Pillai, Vijay, Shetty, Vivek, Sunny, Sumsum P, Suresh, Amritha, Wilder-Smith, Petra, Yadav, Vishal   +12 more
core