Results 231 to 240 of about 844,749 (403)

The mechanism of histone modifications in regulating enzalutamide sensitivity in advanced prostate cancer. [PDF]

Int J Biol Sci
Zhao Z, Jing Y, Xu Z, Zhao H, He X, Lu T, Bai J, Qin W, Yang L.   +8 more
europepmc   +1 more source

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

Advanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du, Muhammad Rafiq, Hui Yuan, Xiangmin Li, Sheng Wang, Jun Wu, Jinfeng Wei, Ren‐Ke Li, Huiming Guo, Burton B Yang   +9 more
wiley   +1 more source

Histone modifications in the regulation of erythropoiesis. [PDF]

Ann Med
Wu X, Xu H, Xia E, Gao L, Hou Y, Sun L, Zhang H, Cheng Y.   +7 more
europepmc   +1 more source

The Histones

, 1962
D. M. P. Phillips
openalex   +1 more source

The roles of DNA, RNA and histone methylation in ageing and cancer

Nature reviews. Molecular cell biology, 2019
Ewa M Michalak, M. Burr, Andrew J. Bannister, M. Dawson   +3 more
semanticscholar   +1 more source

The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds

Advanced Science, EarlyView.
PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal, Pei Y. Liu, Janith Seneviratne, Antoine De Weck, Pooja Venkat, Chelsea Mayoh, Jing Wu, Jesper Maag, Jingwei Chen, Matthew Wong, Nenad Bartonicek, Poh Khoo, Lei Jin, Louise E. Ludlow, David S. Ziegler, Toby Trahair, Pieter Mestdagh, Belamy B. Cheung, Jinyan Li, Marcel E. Dinger, Ian Street, Xu D. Zhang, Glenn M. Marshall, Tao Liu   +23 more
wiley   +1 more source

The role of lysine-rich histone in the maintenance of chromatin structure in metaphase chromosomes.

, 1968
A. E. Mirsky, Carolyn J. Burdick, Eric H. Davidson, Virginia C. Littau   +3 more
openalex   +1 more source

SYMPOSIUM: SYNTHETIC PROCESSES IN THE CELL NUCLEUS. I. HISTONE SYNTHESIS IN NON-REPLICATING CHROMOSOMES [PDF]

, 1962
David P. Bloch
openalex   +1 more source

SIRT4 Promotes Pancreatic Cancer Stemness by Enhancing Histone Lactylation and Epigenetic Reprogramming Stimulated by Calcium Signaling

Advanced Science, EarlyView.
As a downstream target of α2δ1‐mediated calcium signaling, SIRT4 serves as an oncogene to promote the stemness of pancreatic cancer via deacetylating ENO1 directly at K358, leading to attenuated ENO1's RNA‐binding capacity, enhanced glycolytic substrate 2‐PG binding and robust glycolytic activity to increase the level of lactate that induce histone ...
Mengzhu Lv, Xiaodan Yang, Congcong Xu, Qingru Song, Hailian Zhao, Tianjiao Sun, Jingtao Liu, Yuan Zhang, Guogui Sun, Yuanchao Xue, Zhiqian Zhang   +10 more
wiley   +1 more source

Development of a BiAD Sensor for Locus-Specific Detection of Cellular Histone Acetylation Dynamics by Fluorescence Microscopy. [PDF]

Genes (Basel)
Köhler AR, Gutekunst N, Harsch A, Bashtrykov P, Jeltsch A.   +4 more
europepmc   +1 more source