Aberrant histone modifications in pediatric brain tumors
Frontiers in OncologyEpigenetic modifications, particularly histone post-translational modifications (PTMs), are central to pediatric brain tumor pathogenesis, impacting chromatin structure, gene expression, and genomic stability.
Erin T. Hamanishi +10 more
doaj +1 more source
JMJ Histone Demethylases Balance H3K27me3 and H3K4me3 Levels at the HSP21 Locus during Heat Acclimation in Arabidopsis. [PDF]
Biomolecules, 2021 Yamaguchi N, Ito T.
europepmc +1 more source
Supplementary Figure S7 from <i>(R)</i>-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in <i>IDH</i>-Mutant Cancers [PDF]
, 2023 Kathryn Gunn +17 more
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Domestication‐Selected Promoter Insertion in WRKY17 Increases Cadmium Sensitivity in Apple
Plant Biotechnology Journal, EarlyView.ABSTRACT With increasing industrialisation and human activities, heavy metal pollution has become a serious environmental concern, particularly cadmium (Cd) contamination. This study reveals significant differences in Cd tolerance between wild apple (Malus spp.) and cultivated apple (Malus domestica).
Chanyu Wang +15 more
wiley +1 more source
Supplementary Figure S1 from <i>(R)</i>-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in <i>IDH</i>-Mutant Cancers [PDF]
, 2023 Kathryn Gunn +17 more
openalex +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Ty Shitanaka +6 more
wiley +1 more source
Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts [PDF]
Ming Jin +15 more
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The histone demethylase KDM2B activates FAK and PI3K that control tumor cell motility [PDF]
, 2020 Nefeli Zacharopoulou +9 more
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RrMYB2 Regulates Drought Stress via RrJMJ12‐Dependent Epigenetic Modification in Rosa rugosa
Plant Biotechnology Journal, EarlyView.ABSTRACT Rosa rugosa (R. rugosa), an economically important crop valued for its fragrance and medicinal properties, is highly susceptible to drought stress under open‐field cultivation. However, the molecular mechanisms underlying its drought response remain largely unexplored.
Mengjuan Bai +9 more
wiley +1 more source
IOX1 Suppresses Wnt Target Gene Transcription and Colorectal Cancer Tumorigenesis through Inhibition of KDM3 Histone Demethylases. [PDF]
Mol Cancer Ther, 2021 Hoyle RG, Wang H, Cen Y, Zhang Y, Li J.
europepmc +1 more source