Results 251 to 260 of about 197,157 (312)

Inhibition of the Histone Demethylase LSD1 Combined with Caloric Restriction or IGF1/Insulin Inhibition Leads to Durable Responses in a Preclinical Model of Acute Myeloid Leukemia

, 2015
Luca Mazzarella, Tiphanie Durfort, Rani Pallavi, Elena Mylonas, Paolo Falvo, Anna Giulia Sanarico, Massimo Stendardo, Luciano Giacò, Anna Russo, Lucilla Luzi, Massimiliano Mazza, Giulia De Conti, Paola Vianello, Pier Luigi Rossi, Elena Ceccacci, Mohamed Elgendy, Marco Giorgio, Ciro Mercurio, Saverio Minucci, Pier Giuseppe Pelicci   +19 more
openalex   +2 more sources

Targeted inhibition of KDM6 histone demethylases eradicates tumor-initiating cells via enhancer reprogramming in colorectal cancer. [PDF]

Theranostics, 2020
Zhang J, Ying Y, Li M, Wang M, Huang X, Jia M, Zeng J, Ma C, Zhang Y, Li C, Wang X, Shu XS.   +11 more
europepmc   +1 more source

Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase

, 2012
Elena M. Sánchez‐Fernández, Hanna Tarhonskaya, Khalid Al‐Qahtani, Richard J. Hopkinson, James McCullagh, Christopher J. Schofield, Emily Flashman   +6 more
openalex   +1 more source

Histone demethylases and their roles in cancer epigenetics.

Journal of medical oncology and therapeutics, 2016
Alexandra D'Oto, Q. Tian, A. Davidoff, Jun J. Yang   +3 more
semanticscholar   +1 more source

Supplementary Data: list of figures and tables from (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers

Kathryn Gunn, Matti Myllykoski, John Z. Cao, Manna Ahmed, Bofu Huang, Betty Rouaisnel, Bill H. Diplas, Michael M. Levitt, Ryan Looper, John G. Doench, Keith L. Ligon, Harley I. Kornblum, Samuel K. McBrayer, Hai Yan, Cihangir Duy, Lucy A. Godley, Peppi Koivunen, Julie-Aurore Losman   +17 more
openalex   +1 more source

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

Cell, 2016
Carsten Merkwirth, Virginija Jovaisaite, Jenni Durieux, O. Matilainen, S. Jordan, Pedro M. Quirós, Kristan K. Steffen, Evan G. Williams, L. Mouchiroud, Sarah U. Tronnes, Virginia Murillo, Suzanne C. Wolff, R. Shaw, J. Auwerx, A. Dillin   +14 more
semanticscholar   +1 more source

The effects of 2-hydroxyglutarate on the tumorigenesis of gliomas [PDF]

, 2018
Klein, Andreas, Reiter-Brennan, Cara, Semmler, Lukas   +2 more
core   +1 more source

Histone Lysine Demethylase 5A Promotes the Proliferation and Inhibits the Apoptosis of B Cells in SLE

, 2022
Jie Fan, Kaimin Zhang, Farooq Riaz, Yiping Hu, Jinjun Liu, Qinwen Wang, Fan Pan   +6 more
openalex   +1 more source

Mechanistic studies on histone demethylases and related enzymes

, 2013
Richard J. Hopkinson
openalex   +1 more source

Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.

Current Opinion in Genetics and Development, 2016
K. Arcipowski, C. Martinez, P. Ntziachristos   +2 more
semanticscholar   +1 more source