Results 231 to 240 of about 245,589 (335)

The Epigenomic Impact of Quantum Dots: Emerging Biosensors and Potential Disruptors. [PDF]

Epigenomes
Chand A, Kim K.
europepmc   +1 more source

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

Advanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng, Metoboroghene Mowoe, Wenqing Hou, Daniel W. Hagey, Koshi Imami, Samir EL Andaloussi   +5 more
wiley   +1 more source

Cell-cycle-dependent repression of histone gene transcription by histone H4. [PDF]

Nat Struct Mol Biol
Ahmad K, Wooten M, Takushi BN, Vidaurre V, Chen X, Henikoff S.   +5 more
europepmc   +1 more source

Domain cross-talk in regulation of histone modifications: Molecular mechanisms and targeting opportunities

, 2020
James E. Longbotham, Meng Yao Zhang, Danica Galonić Fujimori   +2 more
openalex   +2 more sources

IMPACT OF GLUCOSE METABOLITES ON HISTONE MODIFICATIONS AND GLYOXALASE ACTIVITY IN TROPHOBLAST CELLS [PDF]

, 2017
Tom Seeling, Katarzyna J. Grybel, Mareike Pendzialek, Axel Imhof, Ignasi Forné, Anne Navarrete Santos, Alan M. Simm, Anne Navarrete Santos   +7 more
openalex   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

Advanced Science, EarlyView.
ABSTRACT The cytosine (C) modifications 5‐methylcytosine (mC) and 5‐hydroxymethylcytosine (hmC) are central regulatory elements of mammalian genomes. Both marks occur in double‐stranded DNA in either strand‐symmetric or ‐asymmetric fashion, but it is still poorly understood how this symmetry information is selectively read out by the nuclear proteome ...
Lena Engelhard, Zeyneb Vildan Cakil, Marlon S. Zambrano‐Mila, Simone Eppmann, Tye Gonzalez, Rasmus Linser, Petra Janning, Sidney Becker, Daniel Summerer   +8 more
wiley   +1 more source

Chromatin Regulation of HSV Gene Transcription. [PDF]

Viruses
Zheng Y, Zhang J, Pan D.
europepmc   +1 more source

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source

Breaking Boundaries in Histone Modification MS-Based Detection: A Tailored Search Strategy for Unrestricted Identification of Novel Epigenetic Marks. [PDF]

Mol Cell Proteomics
Vai A, Noberini R, Graziadei A, Polasky DA, Yu F, Nesvizhskii AI, Bonaldi T.   +6 more
europepmc   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source