Results 11 to 20 of about 326,212 (268)

Gallbladder Adenocarcinoma, Potential Target for Anti-Her-2 Therapy

Acta Medica Iranica, 2020
Her-2 (ErbB-2) is an oncogene frequently overexpressed in breast and gastric adenocarcinomas, and anti-Her-2 targeted therapy can be given to such patients.
Ghazi Zafar, Sameen Afzal, Asma Zafar, Samina Zaman   +3 more
doaj   +1 more source

Clinical and prognostic profile of Her2neu positive (non-luminal) intrinsic breast cancer subtype: comparison with Her2neu positive luminal breast cancers

BMC Research Notes, 2018
Objective Her2neu receptor is proto-oncogene which can be over-expressed in both luminal and non-luminal breast cancers. In the present study, we aimed to compare the prognostic and predictive factors like tumor grade, T-stage, N-stage and ki67 index in ...
Atif Ali Hashmi, Raeesa Mahboob, Saadia Mehmood Khan, Muhammad Irfan, Mariam Nisar, Narisa Iftikhar, Maham Siddiqui, Naveen Faridi, Amir Khan, Muhammad Muzzammil Edhi   +9 more
doaj   +1 more source

Detection of immunoglobulins and complement components in formalin fixed and paraffin embedded renal biopsy material by immunoflourescence technique [PDF]

Journal of Nephropathology, 2012
Background: The technique of direct immunoflourescence (IF) is essential in the accurate diagnosis of renal glomerular diseases. The optimal results are obtained when the procedure is done on fresh frozen tissue (IF-F).
Muhammed Mubarak, Javed I Kazi, Umme Kulsoom, Muhammed Ishaque   +3 more
doaj   +1 more source

Histopathology and the future [PDF]

Journal of Clinical Pathology, 1970
A plea is made for a revolution in diagnostic histopathology. In the present account a brief analysis is given of the drawbacks to existing methods used in the histopathological laboratory and suggestions are made for research in those methods which could lead to progress in the speed and sensitivity of diagnosis and to great economies in ...
openaire   +2 more sources

Correlation of Histology of Vesiculobullous Disorders With Immunofluorescence: A Study at A Tertiary Care Centre [PDF]

National Journal of Laboratory Medicine, 2018
Introduction: Vesiculobullous disorders present with varied clinical manifestations. Vesicles and bullae are fluid filled cavities present within or beneath the epidermis.
Sarwat Fatma, Swetha Narla, Sheba Jacob, N Geetha   +3 more
doaj   +1 more source

Mismatch repair deficiency screening in colorectal carcinoma by a four-antibody immunohistochemical panel in Pakistani population and its correlation with histopathological parameters

World Journal of Surgical Oncology, 2017
Background Microsatellite instability (MSI) operates as the second major pathway in the colorectal carcinogenesis. Although genetic testing remains the gold standard for the detection of MSI, the College of American Pathologists (CAP) recommends an ...
Atif Ali Hashmi, Rabia Ali, Zubaida Fida Hussain, Naveen Faridi, Erum Yousuf Khan, Syed Muhammad Abu Bakar, Muhammad Muzzammil Edhi, Mehmood Khan   +7 more
doaj   +1 more source

Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation

World Journal of Surgical Oncology, 2023
Background Breast cancer is the most common tumor in women worldwide. Diabetes mellitus is a global chronic metabolic disease with increasing incidence. Diabetes mellitus has been reported to positively regulate the development of many tumors.
Xiao Cheng, Xiupeng Jia, Chunnian Wang, Shangyan Zhou, Jiayi Chen, Lei Chen, Jinping Chen   +6 more
doaj   +1 more source

Immune and genomic signatures in oral (head and neck) cancer

Heliyon, 2018
Head and neck squamous cell carcinoma (HNSCC) is responsible for a large number of deaths each year. Oral cancer is the most frequent subtype of HNSCC.
Prasenjit Chakraborty, Tanusri Karmakar, Neeraj Arora, Geetashree Mukherjee   +3 more
doaj   +1 more source

Hypoxia-regulated carbonic anhydrase IX (CAIX) protein is an independent prognostic indicator in triple negative breast cancer

Breast Cancer Research, 2022
Background The effect of extracellular microenvironment (hypoxia and pH) has been regarded as a key hallmark in cancer progression. The study aims to investigate the effects of carbonic anhydrase IX (CAIX), a key hypoxia-inducible marker, in triple ...
Chong Hui Clara Ong, Dong Yeul Lee, Bernett Lee, Huihua Li, Jeffrey Chun Tatt Lim, Johnathan Xiande Lim, Joe Poh Sheng Yeong, Hiu Yeung Lau, Aye Aye Thike, Puay Hoon Tan, Jabed Iqbal   +10 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source