Results 11 to 20 of about 423,247 (316)

Hypoacetylation of acetyl-histone H3 (H3K9ac) as marker of poor prognosis in oral cancer

, 2021
Epigenetics refers to changes in cell characteristics that occur independently of modifications to the DNA sequence. Oral carcinogenesis is influenced by modifications in epigenetic mechanisms, including changes in histones, which are proteins that ...
Webber, Liana P., Curra, Marina, Wagner, Vivian P., Squarize, Cristiane H., Martins, Manoela D., Vargas, Pablo A., Castilho, Rogerio M., Meurer, Luise, Carrard, Vinicius C.   +8 more
core   +1 more source

Tumor localization in tissue microarrays using rotation invariant superpixel pyramids [PDF]

, 2015
Tumor localization is an important component of histopathology image analysis; it has yet to be reliably automated for breast cancer histopathology. This paper investigates the use of superpixel classification to localize tumor regions.
Akbar, Shazia, Thompson, Alastair M., Stephen J. McKenna, Shazia Akbar, Alastair M. Thompson, Jordan, Lee, Lee Jordan, McKenna, Stephen J.; id_orcid   +7 more
core   +1 more source

Gallbladder Adenocarcinoma, Potential Target for Anti-Her-2 Therapy

Acta Medica Iranica, 2020
Her-2 (ErbB-2) is an oncogene frequently overexpressed in breast and gastric adenocarcinomas, and anti-Her-2 targeted therapy can be given to such patients.
Ghazi Zafar, Sameen Afzal, Asma Zafar, Samina Zaman   +3 more
doaj   +1 more source

Multiple instance cancer detection by boosting regularised trees [PDF]

, 2015
We propose a novel multiple instance learning algorithm for cancer detection in histopathology images. With images labelled at image-level, we rst search a set of region-level prototypes by solving a submodular set cover problem.
Stephen J. McKenna, Li, Wenqi, Zhang, Jianguo, Jianguo Zhang, McKenna, Stephen; id_orcid, Wenqi Li   +5 more
core   +1 more source

Histopathology and the future [PDF]

Journal of Clinical Pathology, 1970
A plea is made for a revolution in diagnostic histopathology. In the present account a brief analysis is given of the drawbacks to existing methods used in the histopathological laboratory and suggestions are made for research in those methods which could lead to progress in the speed and sensitivity of diagnosis and to great economies in ...
openaire   +2 more sources

Detection of immunoglobulins and complement components in formalin fixed and paraffin embedded renal biopsy material by immunoflourescence technique [PDF]

Journal of Nephropathology, 2012
Background: The technique of direct immunoflourescence (IF) is essential in the accurate diagnosis of renal glomerular diseases. The optimal results are obtained when the procedure is done on fresh frozen tissue (IF-F).
Muhammed Mubarak, Javed I Kazi, Umme Kulsoom, Muhammed Ishaque   +3 more
doaj   +1 more source

Masked crystalline light chain tubulopathy and podocytopathy with focal segmental glomerulosclerosis: a rare MGRS‐associated renal lesion [PDF]

, 2021
Monoclonal Gammopathy of Renal Significance (MGRS) encompasses a wide spectrum of histopathology. Characterizing rare forms of MGRS-related renal pathology remains work in progress.
Candice Roufosse, Linda Moran, Blakey, Sarah, Chaidos, Aristeidis, Stephen Mcadoo, Andreas Kousios, Atta, Maria, Maria Atta, Mcadoo, Stephen, Aristeidis Chaidos, Roufosse, Candice, Moran, Linda, Tam, Frederick Wk, H Terence Cook, Kousios, Andreas, Cook, H Terence, Frederick W K Tam, Sarah Blakey   +17 more
core   +1 more source

Clinical and prognostic profile of Her2neu positive (non-luminal) intrinsic breast cancer subtype: comparison with Her2neu positive luminal breast cancers

BMC Research Notes, 2018
Objective Her2neu receptor is proto-oncogene which can be over-expressed in both luminal and non-luminal breast cancers. In the present study, we aimed to compare the prognostic and predictive factors like tumor grade, T-stage, N-stage and ki67 index in ...
Atif Ali Hashmi, Raeesa Mahboob, Saadia Mehmood Khan, Muhammad Irfan, Mariam Nisar, Narisa Iftikhar, Maham Siddiqui, Naveen Faridi, Amir Khan, Muhammad Muzzammil Edhi   +9 more
doaj   +1 more source

Mismatch repair deficiency screening in colorectal carcinoma by a four-antibody immunohistochemical panel in Pakistani population and its correlation with histopathological parameters

World Journal of Surgical Oncology, 2017
Background Microsatellite instability (MSI) operates as the second major pathway in the colorectal carcinogenesis. Although genetic testing remains the gold standard for the detection of MSI, the College of American Pathologists (CAP) recommends an ...
Atif Ali Hashmi, Rabia Ali, Zubaida Fida Hussain, Naveen Faridi, Erum Yousuf Khan, Syed Muhammad Abu Bakar, Muhammad Muzzammil Edhi, Mehmood Khan   +7 more
doaj   +1 more source

Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation

World Journal of Surgical Oncology, 2023
Background Breast cancer is the most common tumor in women worldwide. Diabetes mellitus is a global chronic metabolic disease with increasing incidence. Diabetes mellitus has been reported to positively regulate the development of many tumors.
Xiao Cheng, Xiupeng Jia, Chunnian Wang, Shangyan Zhou, Jiayi Chen, Lei Chen, Jinping Chen   +6 more
doaj   +1 more source