Results 51 to 60 of about 698,939 (333)

The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models

Frontiers in Cell and Developmental Biology, 2020
Keloids constitute an abnormal fibroproliferative wound healing response in which raised scar tissue grows excessively and invasively beyond the original wound borders.
G. C. Limandjaja, F. Niessen, R. Scheper, S. Gibbs   +3 more
semanticscholar   +1 more source

Circular RNA UBAP2 contributes to tumor growth and metastasis of cervical cancer via modulating miR-361-3p/SOX4 axis

Cancer Cell International, 2020
Background Increasing researches have reported that circular RNA UBAP2 (circUBAP2) may be a potential prognosis biomarker and participate in the development of several cancers; however, the role of circUBAP2 in cervical cancer (CC) remains largely ...
Lingli Meng, Xiupeng Jia, Wenying Yu, Chunnian Wang, Jie Chen, Fenglei Liu   +5 more
doaj   +1 more source

A Compact Representation of Histopathology Images using Digital Stain Separation & Frequency-Based Encoded Local Projections

, 2019
In recent years, histopathology images have been increasingly used as a diagnostic tool in the medical field. The process of accurately diagnosing a biopsy sample requires significant expertise in the field, and as such can be time-consuming and is prone
AC Ruifrok, Andrew Janowczyk, DG Lowe, F Mendivil, HR Tizhoosh, MN Gurcan, T Ahonen, U Molter   +7 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Predictive Value of Excision Repair Cross Complementation Group 1 (ERCC1) by Immunohistochemistry for Determining Neoadjuvant Chemotherapy Response in Triple-Negative Breast Cancers

The Breast Journal
Conclusion: In this study, we established the role of negative ERCC1 expression in predicting the response to chemotherapy in neoadjuvant TNBC. Therefore, ERCC1 can be used as a predictive marker to stratify patients who will benefit from neoadjuvant ...
Atif Ali Hashmi, Yumna Ajaz, Muhsana Sajjad, Fazail Zia, Muhammad Irfan, Syed Muhammad Abu Bakar, Erum Yousuf Khan, Naveen Faridi   +7 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

SPARC in Breast Carcinomas: A Critical Review

BioMedica, 2020
Breast cancer is the second most common cancer in the world according to World Health Organization statistics. Among Asian countries, Pakistan has the highest incidence of breast cancer. The normal breast development is interplay between various hormones
Waqas Arshad Mughal, Sobia Khalid, Nadia Naseem, AH Nagi   +3 more
doaj   +1 more source

Extramedullary hematopoiesis in an inguinal lymph node: an unusual presentation of primary myelofibrosis

World Journal of Surgical Oncology, 2022
Background Extramedullary hematopoiesis (EMH) is a proliferation of hematopoietic tissue outside of the bone marrow medullary space. It is a pathophysiologic response, more often associated with either a benign reactive hematological disease or a ...
Nausheen Yaqoob, Neelum Mansoor, Hania Naveed, Saba Jamal   +3 more
doaj   +1 more source

Discriminating Different Classes of Toxicants by Transcript Profiling [PDF]

, 2004
Male rats were treated with various model compounds or the appropriate vehicle controls. Most substances were either well-known hepatotoxicants or showed hepatotoxicity during preclinical testing.
Albertini, Silvio, Boess, Franziska, de Vera, Maria Cristina, Gasser, Rodolfo, Ruepp, Stefan, Steiner, Guido, Suter, Laura   +6 more
core   +2 more sources

Breast Cancer Histopathology Image Classification Using an Ensemble of Deep Learning Models

Italian National Conference on Sensors, 2020
Breast cancer is one of the major public health issues and is considered a leading cause of cancer-related deaths among women worldwide. Its early diagnosis can effectively help in increasing the chances of survival rate.
Zabit Hameed, Sofia Zahia, B. Garcia-Zapirain, J. Aguirre, Ana María Vanegas   +4 more
semanticscholar   +1 more source