Results 1 to 10 of about 22,776 (243)

High prevalence and mortality due to Histoplasma capsulatum in the Brazilian Amazon: An autopsy study. [PDF]

PLoS Neglected Tropical Diseases, 2021
BackgroundHistoplasmosis is acquired by inhalation of spores of the dimorphic fungus Histoplasma spp. Although this pathogen is distributed worldwide, it is more prevalent in the Americas.
Natalia Rakislova, Juan Carlos Hurtado, Antonio E M Palhares, Luiz Ferreira, Monique Freire, Marcus Lacerda, Wuelton Monteiro, Mireia Navarro, Isaac Casas, Marcus de Melo Teixeira, Paola Castillo, Maria Teresa Rodrigo-Calvo, Lorena Marimon, José Guerrero, Rosauro Varo, Vima Delgado, Llorenç Quintó, Francesc Marco, Emilio Letang, Jordi Vila, Quique Bassat, Clara Menéndez, Jaume Ordi, Miguel J Martínez   +23 more
doaj   +2 more sources

Sexual Reproduction in Histoplasma capsulatum [PDF]

Mycologia, 1967
Growth of fungi on plates of soil and hair has been found to stimulate many dermatophytes and related fungi to reproduce sexually (5, 8). In our laboratory such studies have led to the discovery of the ascigerous state of: Microsporum cookei Ajello (1)-Nannizzia cajetani Ajello (2); M. vanbreuseghemii Georg, Ajello, Friedman & Brinkman-N. grubyia Georg,
Libero Ajello, Shaochuan Cheng
openalex   +6 more sources

Extracellular superoxide dismutase protects Histoplasma yeast cells from host-derived oxidative stress. [PDF]

PLoS Pathogens, 2012
In order to establish infections within the mammalian host, pathogens must protect themselves against toxic reactive oxygen species produced by phagocytes of the immune system.
Brian H Youseff, Eric D Holbrook, Katherine A Smolnycki, Chad A Rappleye   +3 more
doaj   +6 more sources

Acute Myelopathy as Initial Presentation of Disseminated Histoplasmosis: A Case Report. [PDF]

Case Rep Infect Dis
Histoplasmosis is a fungal infection caused by the fungus Histoplasma capsulatum that can rarely present with central nervous system (CNS) manifestations that include meningitis, encephalitis, focal brain or spinal cord lesions, and stroke syndromes. Because of this variation from patient to patient, CNS histoplasmosis is a difficult clinical diagnosis
Blackbourn L, Yoo E, Lunt MD, Hamid U.
europepmc   +2 more sources

Revealing pathogenesis-associated metabolites in <i>Histoplasma capsulatum</i> through comprehensive metabolic profiling. [PDF]

mSystems
During infection, Histoplasma capsulatum yeasts interact with a variety of phagocytic cells, where macrophages represent an important niche for long-term intracellular fungal survival and replication.
Heckart A, Cocuron J-C, Ray SC, Rappleye CA, Alonso AP.   +4 more
europepmc   +2 more sources

Contribuição ao estudo de Histoplasma capsulatum (Darling, 1906) Contribuition to the study of Histoplasma capsulatum, (Darling, 1906) [PDF]

Memorias do Instituto Oswaldo Cruz, 1972
Usando o meio de amônio-sulfato-glicose, conseguimos que oito amostras estéreis de Histoplasma capsulatum voltassem a produzir estalagmosporos.Using the Amonium sulfate glucose medium we succeed in obtaining stalagmospores in eight sterile strains of ...
M. Carlota Pedroso, N. Callado Marçano
doaj   +2 more sources

Three transporters, including the novel Gai1 permease, drive amino acid uptake in <i>Histoplasma</i> yeasts. [PDF]

Virulence
The dimorphic fungus Histoplasma capsulatum, which almost exclusively resides within host phagocytic cells during infection, must meet its nutritional needs by scavenging molecules from the phagosome environment.
Ray SC, Shen Q, Rappleye CA.
europepmc   +2 more sources

Improvement in Diagnosis of \u3cem\u3eHistoplasma\u3c/em\u3e Meningitis by Combined Testing for \u3cem\u3eHistoplasma\u3c/em\u3e Antigen and Immunoglobulin G and Immunoglobulin M Anti-\u3cem\u3eHistoplasma\u3c/em\u3e Antibody in Cerebrospinal Fluid [PDF]

Clinical Infectious Diseases, 2017
Background. Central nervous system (CNS) histoplasmosis is a life-threatening condition and represents a diagnostic and therapeutic challenge. Isolation of Histoplasma capsulatum from cerebrospinal fluid (CSF) or brain tissue is diagnostic; however ...
Albers, Amanda, Bloch, Karen C., Chow, Felicia C., Davis, Thomas E., Hage, Chadi A., Khairy, Raed N., Myint, Thein, Raymond-Guillen, Luke, Street, Alan C., Wheat, L Joseph, Woc-Colburn, Laila, Wright, Patty W., Yamamoto, Tomotaka   +12 more
core   +8 more sources

A Case Report of Histoplasma-Associated Empyema Treated With Intravenous Injection and Local Thoracic Irrigation of Amphotericin B Plus Medical Thoracoscopy [PDF]

Frontiers in Public Health, 2022
Cases of empyema associated with Histoplasma infection are rarely reported. Here, we discuss a case of Histoplasma-associated empyema successfully treated with amphotericin B intravenous and pleural infusion therapy and multiple medical thoracoscopies. A
Ning Cui, Lijun Wang, Jingming Zhao
doaj   +9 more sources

Biodiverse Histoplasma Species Elicit Distinct Patterns of Pulmonary Inflammation following Sublethal Infection [PDF]

mSphere, 2020
Histoplasma is an endemic dimorphic fungus that can cause disease in healthy and immunocompromised individuals after the transition of inhaled spores into the facultative intracellular yeast form. There is substantial diversity among Histoplasma species,
Grant S. Jones, Victoria E. Sepúlveda, William E. Goldman   +2 more
doaj   +5 more sources