Results 41 to 50 of about 21,220 (243)

Characterization of patients with clinical diagnosis of Histoplasmosis in the "Hospital Universitario San Ignacio" between 2012-2016

open access: yesInfectio, 2019
Introduction: Disseminated histoplasmosis is a common presentation in immunosuppressed patients. The introduction of new diagnostic methods and the improvement of the survival of patients with HIV could have changed the clinical characteristics of ...
Isabel Cristina Cuéllar
doaj   +1 more source

Histoplasmosis diseminada progresiva aguda en un paciente inmunocompetente

open access: yesMedicentro, 2021
La histoplasmosis diseminada progresiva constituye una expresión singular y rara de la infección por Histoplasma capsulatum. Sus formas agudas de presentación suelen aparecer en pacientes con deficiencias inmunitarias graves (fundamentalmente VIH).
Nabil Ghaddar Fuentes   +2 more
doaj  

The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure

open access: yesmBio, 2016
The fungal pathogen Histoplasma capsulatum parasitizes host phagocytes. To avoid antimicrobial immune responses, Histoplasma yeasts must minimize their detection by host receptors while simultaneously interacting with the phagocyte.
Andrew L. Garfoot   +4 more
doaj   +1 more source

Cost-effectiveness evaluation of routine histoplasmosis screening among people living with advanced HIV disease in Latin America and the Caribbean.

open access: yesPLOS Global Public Health, 2023
Histoplasma antigen can be detected in people with advanced HIV disease (AHD), allowing for early and accurate diagnosis of histoplasmosis. The aim of this analysis was to assess the cost-effectiveness of routine histoplasmosis screening using antigen ...
Radha Rajasingham   +11 more
doaj   +1 more source

Chromosome-Level Genome Assembly of a Human Fungal Pathogen Reveals Synteny among Geographically Distinct Species

open access: yesmBio, 2022
Histoplasma capsulatum, a dimorphic fungal pathogen, is the most common cause of fungal respiratory infections in immunocompetent hosts. Histoplasma is endemic in the Ohio and Mississippi River Valleys in the United States and is also distributed ...
Mark Voorhies   +10 more
doaj   +1 more source

Histoplasmosis, An Underdiagnosed Disease Affecting People Living With HIV/AIDS in Brazil: Results of a Multicenter Prospective Cohort Study Using Both Classical Mycology Tests and Histoplasma Urine Antigen Detection

open access: yesOpen Forum Infectious Diseases, 2019
Background Histoplasmosis is highly endemic in the American continent. This condition is associated with a high mortality, particularly in people living with HIV/AIDS (PLWHA).
D. Falci   +18 more
semanticscholar   +1 more source

Bilateral adrenal histoplasmosis in a diabetic patient: A case report and review of cases in India

open access: yesApollo Medicine, 2019
Disseminated histoplasmosis usually affects immunocompromised and immunosuppressed individuals and may involve various organ systems of our body. The definitive diagnosis of histoplasmosis is very challenging because it usually presents with nonspecific ...
Hena Butta   +6 more
doaj   +1 more source

Diversification of Fungal Chitinases and Their Functional Differentiation in Histoplasma capsulatum

open access: yesbioRxiv, 2020
Chitinases enzymatically hydrolyze chitin, a highly abundant biomolecule with many potential industrial and medical uses in addition to their natural biological roles.
Kristie D. Goughenour   +3 more
semanticscholar   +1 more source

Biodiverse Histoplasma Species Elicit Distinct Patterns of Pulmonary Inflammation following Sublethal Infection

open access: yesMsphere, 2020
Acute pulmonary histoplasmosis in healthy individuals comprises most of the disease burden caused by the fungal pathogen Histoplasma. Fungal pneumonia is frequently delayed in diagnosis and treatment due to a prolonged period of quiescence early during ...
Grant S. Jones   +2 more
semanticscholar   +1 more source

The power of many: when genetics met yeasts and high‐throughput

open access: yesBiological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

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