Results 61 to 70 of about 22,776 (243)

Establishment of an experimental system to analyse extracellular vesicles during apoplastic fungal pathogenesis

Journal of Extracellular Biology, Volume 4, Issue 2, February 2025.
Abstract Phoma stem canker disease of oilseed rape (Brassica napus) is caused by the extracellular fungal pathogen Leptosphaeria maculans. Although this pathogen resides exclusively in apoplastic spaces surrounding plant cells, the significance of extracellular vesicles (EVs) has not been assessed.
Nathaniel Hearfield, Dominik Brotherton, Zedi Gao, Jameel Inal, Henrik U. Stotz   +4 more
wiley   +1 more source

Targeted gene deletions in the dimorphic fungal pathogen Histoplasma using an optimized episomal CRISPR/Cas9 system

mSphere, 2023
The rapid development of CRISPR/CRISPR-associated (Cas) systems has revolutionized the ability to produce genetic mutations in a desired locus, particularly in organisms with low rates of homologous recombination.
Chad A. Rappleye
doaj   +1 more source

Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium. [PDF]

, 2019
BACKGROUND: Invasive fungal diseases (IFDs) remain important causes of morbidity and mortality. The consensus definitions of the Infectious Diseases Group of the European Organization for Research and Treatment of Cancer and the Mycoses Study Group have ...
Akan, H, Alexander, BD, Andes, D, Azoulay, E, Baddley, JW, Bassetti, M, Bialek, R, Bradsher, RW, Bretagne, S, Calandra, T, Caliendo, AM, Castagnola, E, Chen, SC, Clancy, CJ, Cruciani, M, Cuenca-Estrella, M, Decker, CF, Desai, SR, Donnelly, JP, Fisher, B, Groll, AH, Harrison, T, Heussel, CP, Jensen, HE, Kauffman, CA, Kibbler, CC, Kontoyiannis, DP, Kullberg, B-J, Lagrou, K, Lamoth, F, Lehrnbecher, T, Lockhart, SR, Loeffler, J, Lortholary, O, Maertens, J, Marchetti, O, Marr, KA, Masur, H, Meis, JF, Morrisey, CO, Nucci, M, Ostrosky-Zeichner, L, Pagano, L, Pappas, PG, Patterson, TF, Perfect, JR, Prokop, CS, Racil, Z, Roilides, E, Ruhnke, M, Shoham, S, Slavin, MA, Sorrell, TC, Steinbach, WJ, Stevens, DA, Thompson, GR, Vazquez, JA, Verweij, PE, Viscoli, C, Walsh, TJ, Warris, A, Wheat, LJ, White, PL, Wingard, JR, Zaoutis, TE   +64 more
core   +5 more sources

Assessing the potential risk of human pathogen resistance to medical antifungal treatments arising from agricultural use of fungicides with the same mode of action

Plant Pathology, Volume 74, Issue 2, Page 578-594, February 2025.
A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action. Abstract A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action.
Neil Paveley, Frank van den Bosch, Michael Grimmer   +2 more
wiley   +1 more source

Detection of Histoplasma capsulatum in Bats Dropping by using Polymerase Chain Reaction(PCR) at the First Time in Iraq [PDF]

, 2015
In the present we isolated the fungus Histoplasma capsulatum as a first time from bats dropping in AL-Qadisiyah province .Results show that the macro and micro characteristics referred that these characteristics was related to the fungus Histoplasma ...
Jasim, Neeran Obied
core   +2 more sources

Antimicrobial Peptides: A Promising Alternative to Conventional Antimicrobials for Combating Polymicrobial Biofilms

Advanced Science, Volume 12, Issue 1, January 9, 2025.
Antimicrobial peptides (AMPs) are promising alternatives to conventional treatments for polymicrobial biofilms, which increase pathogen resistance. AMPs disrupt biofilm extracellular matrices and microbial membranes, inhibiting biofilm formation and enhancing antibiotic efficacy. Current research addresses challenges like stability and production costs
Cesar Augusto Roque‐Borda, Laura Maria Duran Gleriani Primo, Kaila Petronila Medina‐Alarcón, Isabella C. Campos, Camila de Fátima Nascimento, Mauro M. S. Saraiva, Angelo Berchieri Junior, Ana Marisa Fusco‐Almeida, Maria José Soares Mendes‐Giannini, João Perdigão, Fernando Rogério Pavan, Fernando Albericio   +11 more
wiley   +1 more source

Reverse genetics through random mutagenesis in Histoplasma capsulatum [PDF]

, 2009
Background The dimorphic fungal pathogen Histoplasma capsulatum causes respiratory and systemic disease in humans and other mammals. Progress in understanding the mechanisms underlying the biology and the pathogenesis of Histoplasma has been hindered by ...
Dougherty, Julie A, Rappleye, Chad A, Youseff, Brian H   +2 more
core   +3 more sources

Comparative transcriptomics and metabolomics provide insight into degeneration‐related physiological mechanisms of Morchella importuna after long‐term preservation

Microbial Biotechnology, Volume 18, Issue 1, January 2025.
Nutrient‐limited medium in combination with avoiding of repeated subculturing during long‐term preservation of Morchella importuna culture was found to be the most beneficial method for maintaining viability and fruiting capability. Metabolic alterations related to sulfur‐containing amino‐acid biosynthesis, DNA repair, and cellular structural ...
Ying Chen, Xuelian Cao, Liyuan Xie, Jie Tang, Lixu Liu, Di Wang, Xiang Wu, Tianhai Liu, Yang Yu, Yong Wang, Francis Martin, Weihong Peng, Hao Tan   +12 more
wiley   +1 more source

Infectious keratitis secondary to Histoplasma capsulatum: the first case reports in humans

Brazilian Journal of Infectious Diseases
The authors report an unusual case of fungal keratitis caused by Histoplasma capsulatum in a male immunocompetent patient. PCR confirmed the presence of the fungus DNA in the material studied.
Enyr S. Arcieri, Ademir Rocha, Camila N. Mendonça, Eduardo G. V. Andreo, Ioná G.A. Finotti, Rafael L. Furlanetto, Rafael S. Arcieri, Flávio J. Rocha, Luiz V. Rizzo   +8 more
doaj   +1 more source

Genome Sequences Reveal Cryptic Speciation in the Human Pathogen Histoplasma capsulatum

mBio, 2017
Histoplasma capsulatum is a pathogenic fungus that causes life-threatening lung infections. About 500,000 people are exposed to H. capsulatum each year in the United States, and over 60% of the U.S. population has been exposed to the fungus at some point
Victoria E. Sepúlveda, Roberto Márquez, David A. Turissini, William E. Goldman, Daniel R. Matute   +4 more
doaj   +1 more source