Three transporters, including the novel Gai1 permease, drive amino acid uptake in Histoplasma yeasts
The dimorphic fungus Histoplasma capsulatum, which almost exclusively resides within host phagocytic cells during infection, must meet its nutritional needs by scavenging molecules from the phagosome environment.
Stephanie C. Ray +2 more
doaj +1 more source
Histoplasmosis and penicilliosis: Comparison of clinical features, laboratory findings and outcome [PDF]
SummaryIntroductionHistoplasmosis and penicilliosis are infections caused by the dimorphic fungi, Histoplasma capsulatum and Penicillium marneffei, respectively.
Mootsikapun, Piroon, Srikulbutr, Sukanya
core +1 more source
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source
Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant‐Associated Infection Surveillance Network ( TRANSNET ) [PDF]
Background Invasive fungal infections are a major cause of morbidity and mortality among solid organ transplant ( SOT ) and hematopoietic cell transplant ( HCT ) recipients, but few data have been reported on the epidemiology of endemic fungal ...
Alexander, B.D. +18 more
core +1 more source
A Novel In Vitro Host−Pathogen Model for Felis catus and Sporothrix Zoonotic Species Investigation
ABSTRACT Hyperendemic zoonotic sporotrichosis, attributed to Sporothrix brasiliensis, presents a significant public health challenge in Brazil. Cats exhibit severe symptoms and high fungal loads, though their susceptibility is unclear. Sporothrix schenckii can also cause feline disease, primarily seen in Asia.
Gabriele Barros Mothé +10 more
wiley +1 more source
Disseminated cutaneous histoplasmosis in an immunocompetent adult
Histoplasmosis, a systemic mycosis caused by the dimorphic fungus Histoplasma capsulatum var capsulatum and Histoplasma capsulatum var duboisii is endemic to many parts of the world.
Manoj Harnalikar +2 more
doaj +1 more source
A survey to determine the occurrence of Histoplasma capsulatum and Cryptococcus neoformons in air-conditioners [PDF]
Call number: LD2668 .T4 1968 B68Master of ...
Botard, Robert William.
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Pichia pastoris Fep1 is a [2Fe-2S] protein with a Zn finger that displays an unusual oxygen-dependent role in cluster binding [PDF]
Fep1, the iron-responsive GATA factor from the methylotrophic yeast Pichia pastoris, has been characterised both in vivo and in vitro. This protein has two Cys(2)-Cys(2) type zinc fingers and a set of four conserved cysteines arranged in a Cys-X-5-Cys-X ...
Battistoni, Andrea +8 more
core +3 more sources
Promising Prodiginins Biological Activities
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto +6 more
wiley +1 more source
Analysis of Hypoxia Response Mechanisms in Histoplasma capsulatum [PDF]
Natural and Mathematical Sciences Poster ForumHistoplasma capsulatum is a dimorphic fungal pathogen endemic to the Ohio River valley. This pathogen is particularly harmful because of its ability to cause disease in both immunocompromised and ...
Dickerhoof, Emily
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