Results 151 to 160 of about 1,368,556 (344)
Mathematics at the eve of a historic transition in biology
, 2017 Guo‐Wei Wei
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
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Historic Caddo Archaeological Sites in Cherokee County, Texas [PDF]
, 2016 The historic archaeology of the Caddo Indian peoples in East Texas has been the subject of considerable interest by Caddo archaeologists for a number of years. Much of that interest has been focused on the investigation of the effects of European contact
Perttula, Timothy K. +2 more
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Historical Explanation and Historical Names
RUDN Journal of Philosophy, 2015 The paper is dedicated to one of the aspects of the problem of the explanation in history, i.e. to an analysis of the contribution of references of names of historical persons, places, events etc. into an explanation in history. An important condition of explanation is the relevancy of what explains to what is explained. The latter is determined by the
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Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
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The Archaeology of Provincial Officers' Huts at Crown Point State Historic Site
, 1995 Charles L. Fisher
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Molecular Oncology, EarlyView.The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat +18 more
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Monitoring and Assessing Structural Damage in Historic Buildings [PDF]
, 2008 Julia Armesto +3 more
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