Results 151 to 160 of about 1,341,883 (294)

Historic Floodplain Meadows in the Landscape: Investigating Anthropogenic Habitats Important for Nature Conservation, Carbon Sequestration and Flood Attenuation. [PDF]

Environ Manage
Firth A, Firth E, Rothero E, Gowing D.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Analyzing the "Opposite" Approach in Additions to Historic Buildings Using Visual Attention Tools: Dresden Military History Museum Case. [PDF]

J Eye Mov Res
Özkaraca Özalp N, Halaç HH, Özalp MF, Bademci F.   +3 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The scenicness of historic buildings rivals that of natural features: evidence from crowdsourced photographs of English urban areas. [PDF]

Front Psychol
Sherborne S, Malthouse E.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Using Historic and Contemporary Genomes to Assess the Genetic Consequences of a Population Decline in an Endangered Tern Population. [PDF]

Evol Appl
Schnelle A, Rollins RE, Müller IA, Irestedt M, Cecere JG, Serra L, Gutiérrez JS, Masero JA, Risch M, Bouwhuis S, Liedvogel M.   +10 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Application of Digitizing Methods to Urban Area with an Example-- Zong-Ye Historic District, Tainan City [PDF]

This article attempts to apply digitizing methods to historic assets in old downtown by map overlaying analysis after map rectifying, and then taking textual method through surveying images.
Chen Chengche, Cheng Hsienhsin
core  

Incorporating historic information to further improve power when conducting Bayesian information borrowing in basket trials. [PDF]

Biostatistics
Daniells L, Mozgunov P, Barnett H, Bedding A, Jaki T.   +4 more
europepmc   +1 more source