Results 131 to 140 of about 1,348,303 (315)

Legacy and Springboard: The Untapped Potential of Archaeological Archives for Scientific Innovation

open access: yesInternet Archaeology
Archaeological archives form a public resource that enables the reinterpretation of original findings from archaeological investigations, provides the raw material for further research, informs museum displays and teaching collections, and gives society ...
Barney Sloane
doaj   +1 more source

If They Can Raze it, Why Can\u27t I? A Constitutional Analysis of Statutory and Judicial Religious Exemptions to Historic Preservation Ordinances [PDF]

open access: yes, 2007
In 1996, America almost lost a great piece of its history. The Cathedral of Saint Vibiana, located in Los Angeles, was in danger of being destroyed. The Baroque-inspired Italianate structure was completed in 1876 by architect Ezra F. Kysor.
Guiffre, Erin
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Pomham Rocks Lighthouse: Reuse and Rehabilitation Feasibility Report [PDF]

open access: yes, 2012
The lighthouse has withstood the passing of time, including the harsh coastal weather elements. Pomham Rocks’ significance was obtained through its historic function, architectural style and keeper history.
Caruso, Nina   +3 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A Case Study on the Reuse of Digital Archaeological Data: An Analysis of the Atlas of Hillforts of Britain and Ireland

open access: yesJournal of Computer Applications in Archaeology
The Atlas of Hillforts of Britain and Ireland is a large open dataset published online for reuse and reinterpretation. This data is large and complex, making it challenging to manipulate, especially in a discipline where a lack of data literacy skills is
Mike Middleton
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Historic preservation meets community development [PDF]

open access: yes
For years, community development and historic preservation operated in their own worlds. Today a new awareness of common interests is enabling collaborations that produce benefits for all.Community development ; Historic ...
Kennedy Lawson Smith
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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