Results 111 to 120 of about 659,648 (296)

Heritage and Social Prescribing - Historic England's learnings from pilots and collaborative work across sectors 2023-2024

open access: yesInternet Archaeology
The last five years have seen an increased awareness and growing evidence about the potential of social prescribing to help address health inequalities and help take some of the pressures off the National Health Service (NHS). Consequently, more and more
Desi Gradinarova
doaj   +1 more source

HISTORICAL [PDF]

open access: yesBritish Journal of Ophthalmology, 1946
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Transforming lives through archaeology: civil society, social justice and heritage

open access: yesInternet Archaeology
This article discusses the need for protective factors for health and wellbeing through heritage and archaeology-led practice, and the range of benefits attributed to such practice in specific circumstances working with communities with unmet needs.
Linda Monckton
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

1998 Guide to Funding Resources for Historic Preservation

open access: yes, 1998
This document is a directory of potential funding sources for historic preservation and other related fields. Potential funding sources include national organizations, federal and state funds, regional funding sources, private foundations, corporate ...

core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

New Jersey Historic Preservation Office Brochure

open access: yes, 2003
This brochure is intended to provide information about the New Jersey Historic Preservation Office and to encourage the preservation of historical resources in New Jersey.

core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Home - About - Disclaimer - Privacy