Results 91 to 100 of about 1,348,303 (315)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Energy Costs of Historic Preservation [PDF]
, 2017 We explore the impact of historical preservation policies on domestic energy consumption. Using panel data for England from 2006 to 2013 and employing a fixed effects strategy, we document that (i) rising national energy prices induce an increase in home
Hilber, C., Palmer, C., Pinchbeck, E.
core
Affordances of Historic Urban Landscapes: an Ecological Understanding of Human Interaction with the Past [PDF]
, 2014 Heritage has been defined differently in European contexts. Despite differences, a common challenge for historic urban landscape management is the integration of tangible and intangible heritage. Integration demands an active view of perception and human-
Alves, Susana
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Digital Archaeological Heritage: an introduction
Internet Archaeology, 2017 The 17th EAC Symposium (Europae Archaeologiae Consilium) in Brighton was convened under a concept note that recognised that 'Digital technologies are developing at an unprecedented speed.
Keith May
doaj +1 more source
Funding Culture: An Analysis of Historic Site Preservation Policy
, 2020 This paper examines the way in which public funding and tax policies are applied to federally recognized historic preservation sites and how that application influences the a variety of stakeholder communities including tax payers, historical ...
Grab, Ann L.
core
Book Reviews: Thinking About Cultural Resource Management: Essays From the Edge [PDF]
, 2003 The Guru of Section 106 has just compiled a book of essays that every CRM professional, archeologist, anthropologist, historic preservationist, environmentalist (have I covered all the pertinent “ists”?), and Native Americans concerned with preserving ...
Cast, Robert
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Capturing the Material Invisible: OGS Crawford, Ghosts, and the Stonehenge Avenue
Bulletin of the History of Archaeology, 2016 Why do archaeologists excavate? What should we expect from archaeological archives? OGS Crawford’s discovery and excavation of the course of the Stonehenge Avenue in the summer of 1923 – perhaps the first time that a cropmark was identified on an aerial ...
Martyn Barber
doaj +1 more source