Results 71 to 80 of about 659,648 (296)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Untangling Historical Injustice and Historical Ill
, 2009 Intergenerational Justice Review, Vol 1, No 1 (2009): Historical ...
openaire +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The Impact of Age on the Value of historic homes in a Nationally Recognized Historic District [PDF]
This paper uses hedonic modeling to test the effects of age, both actual and effective, on the value of historic properties within a nationally recognized historic district.
Dawn Jourdan +2 more
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Making Choices: Valletta, Development, Archaeology and Society
Internet Archaeology, 2018 The European Archaeological Council's working group on 'Making Choices' conducted a survey of EAC member states about the ways in which they make decisions in archaeological heritage management with particular reference to development-led archaeological ...
Barney Sloane
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Historic Designation and Residential Property Values [PDF]
The State of California enacted the Mills Act in 1972. This act allows local municipalities the option of setting up a historic designation program.
Charles Tu +2 more
core
Scandinavian Journal of Primary Health CareBackground Since its academic inception in the 1960s, Germany’s general practice has seen numerous dissertations, many of which are housed in the ‘Archive of German language General Practice’ (ADAM).Aim This study aims to provide the first comprehensive ...
Nora Sosna, Jost Steinhäuser
doaj +1 more source