Results 81 to 90 of about 1,341,883 (294)

Historical publications of the Institut d’Estudis Catalans during 2022

open access: yesCatalan Historical Review, 2023
Published by the History and Archeology Section and its Affiliated Societies
Oficina d'Assessorament Històric - Institut d'Estudis Catalans
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Making Choices: Valletta, Development, Archaeology and Society

open access: yesInternet Archaeology, 2018
The European Archaeological Council's working group on 'Making Choices' conducted a survey of EAC member states about the ways in which they make decisions in archaeological heritage management with particular reference to development-led archaeological ...
Barney Sloane
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Understanding and controlling the ingress of driven rain through exposed, solid wall masonry structures [PDF]

open access: yes, 2014
Long term performance of historic buildings can be affected by many environmental factors, some of which become more apparent as the competence of the fabric deteriorates.
Bowler   +5 more
core   +1 more source

Exploring general practice research in Germany: a systematic review of dissertation topics from 1965–2023

open access: yesScandinavian Journal of Primary Health Care
Background Since its academic inception in the 1960s, Germany’s general practice has seen numerous dissertations, many of which are housed in the ‘Archive of German language General Practice’ (ADAM).Aim This study aims to provide the first comprehensive ...
Nora Sosna, Jost Steinhäuser
doaj   +1 more source

Historical Perspectives

open access: yes, 2010
The phenomenon of yawning is just as intriguing and fascinating as sleep, yet understanding of its causes and consequences has defied the human mind for centuries. Hippocrates, Sennert, Boerhaave and de Gorter each advanced a theory in his time. From the release of tainted humor to the awakening of animal spirits and improved brain oxygenation, the ...
openaire   +2 more sources

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

'Do I really need to dig it?' — Making Choices in Development-Led Archaeological Excavation in Northern Ireland

open access: yesInternet Archaeology, 2018
Most excavations in Northern Ireland arise from new development or land-use change proposals. The requirement to mitigate usually results in an excavation of sub-surface remains, with a nuanced approach in dealing with urban, peri-urban and rural sites ...
John D.J. O'Keeffe
doaj   +1 more source

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