Results 81 to 90 of about 1,368,556 (344)
Research Data Management in a Cultural Heritage Organisation
International Journal of Digital Curation, 2020 Research is a core function of cultural heritage organisations. Inevitably, the undertaking of research by galleries, libraries, archives and museums (the GLAM sector) leads to the creation of vast quantities of research data.
Tom Drysdale
doaj +1 more source
Now the wars are over: The past, present and future of Scottish battlefields [PDF]
, 2010 Battlefield archaeology has provided a new way of appreciating historic battlefields. This paper provides a summary of the long history of warfare and conflict in Scotland which has given rise to a large number of battlefield sites.
C Duffy +23 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Making Choices: Valletta, Development, Archaeology and Society
Internet Archaeology, 2018 The European Archaeological Council's working group on 'Making Choices' conducted a survey of EAC member states about the ways in which they make decisions in archaeological heritage management with particular reference to development-led archaeological ...
Barney Sloane
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Organizing and Indexing Photo Collections [PDF]
, 2012 Historical photo archives or collections can put an organization on the map and make it into a destination for patrons. Conversely, if not well organized and indexed, collections and archives can languish in obscurity and occupy valuable space and ...
Fortier, Rose
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Nations, Overlapping Generations and Historic Injustice [PDF]
, 2006 This article considers the question of the responsibility that present day generations bear as a result of the actions of their ancestors. Is it morally significant that we share a national identity with those responsible for the perpetration of historic
Butt, Daniel
core
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Internet Archaeology, 2018 Most excavations in Northern Ireland arise from new development or land-use change proposals. The requirement to mitigate usually results in an excavation of sub-surface remains, with a nuanced approach in dealing with urban, peri-urban and rural sites ...
John D.J. O'Keeffe
doaj +1 more source