Results 71 to 80 of about 482,315 (310)
Merging Special Collections with GIS Technology to Enhance the User Experience [PDF]
, 2016 This analysis evaluates how PhillyHistory.org merged their unique special collection materials with geospatial-based progressive technology to challenge and educate the global community.
Nichols, Gina L
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Historic Cities Project Task 4 – The Business Surveys: Questionnaire Design, Implementation and Initial Analysis. [PDF]
, 2005 The Historic Cities project examined the potential impacts of transport demand management strategies on three case study ‘historic’ cities in England. These cities are York, Cambridge and Norwich, all of which have the following characteristics: - they ...
Jopson, A., Still, B.
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
TO THE SOURCES OF DIACHRONIC SOCIOLINGUISTICS: GLOBAL EXPERIENCE AND UKRAINIAN PROBLEMATICS
Записки з українського мовознавства, 2017 The subject of the suggested research is a new sphere of sociolinguistics – diachronic sociolinguistics: its sources, subject of the research and tasks.
І. Д. Фаріон
doaj +1 more source
Library Cartoons: A Literature Review of Library-themed Cartoons, Caricatures, and Comics [PDF]
, 2013 To understand differing views of past events, historians, political science scholars, and sociologists have analyzed political and editorial cartoons with themes ranging from elections to fiscal policy to human rights.
Chambers, Julia B.
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Nursing research: historical background and teaching information strategies.
Bulletin of the Medical Library Association, 1986 The expansion of research-based literature is one of the foremost goals of the nursing profession. Linked to this goal are the utilization and further development of nursing libraries. This paper discusses some historical factors that have influenced nursing literature. It presents a model for teaching graduate nursing students the relationship between
J M, Sarkis, V L, Conners
openaire +1 more source