Results 181 to 190 of about 7,049,835 (311)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Structured knowledge representation of the South China Sea: An LLM-based knowledge graph approach. [PDF]

PLoS One
Zhao R, Han Z, Liu H.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The unsung heroes of traditional healers in healing and traditional medicine in dementia care for Indigenous populations in North America: an exploration of a compassionate, community-led care model. [PDF]

Front Public Health
Shrestha HL, Shrestha L, Rosich RM, Splaine M, Petahtegoose A.   +4 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A framework on urban design strategies for sustainability of cultural and historical heritage in urban landscape

, 2007
5th WSEAS International Conference on Environment, Ecosystems and Development -- DEC 14-16, 2007 -- Puerto de la Cruz, SPAINCultural heritage is the accumulation of tangible and intangible values stemming from human creativity and interaction between ...
Cetinkale, Sevgi Gormus, Donmez, Sirin, Koçan, Nurhan, Ikiz, Emine, Çelikyay, Hatice Selma, Aydin, Pinar   +5 more
core  

Traditional Islam in Kazakhstan: historical formation, state discourse, and contemporary challenges. [PDF]

Front Sociol
Kerim S, Kurmanaliyev M.
europepmc   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Stakeholder-based assessment of historical urban landscapes as cultural heritage within the context of sustainable development: a case study of İznik (Nikaia). [PDF]

Sci Rep
Kapuci U, Cengiz C, Smardon RC, Cengiz B.   +3 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source