Results 151 to 160 of about 140,262 (309)
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
CULTURAL TOURISM IN A GREEK INSULAR COMMUNITY: THE RESIDENTS’ PERSPECTIVE
Cultural tourism constitutes an alternative strategy of sustainable local development for improving quality of life. The main objective of this type of tourism is to transform the regions, which are characterized by cultural resources, into ideal places ...
Sdrali, Despina, Chazapi, Katerina
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Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
The historical imagination of Christopher Dawson
Christopher Dawson (1889-1970) was one of his generation's most important historians and religious thinkers, and was a significant influence on many contemporaries including T.S. Eliot, C.S. Lewis, and Russell Kirk. This dissertation is a study of his
Sproviero, Glen A.
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A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Formal schooling and self construction: a historical-cultural narrative approach [PDF]
Mata Benítez, Manuel de La +4 more
core
Creation of Educational 3D visualisations of a cultural world Heritage Site: Saltaire Case Study
A world heritage site consists of cultural, archaeological and historic site which includes monuments, buildings, lake, forest and geographical structures as well as cities which have significance importance.
Pande, Preeti
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The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Sustainable urban planning patterns and techniques in historical contextsCase study (Bolaghi neighborhood of Qazvin) [PDF]
Historical contexts have rich cultural and cultural resources and are not very important not only because of the existence of valuable historical buildings and spaces, but also because they are real narratives of the life and activities of human beings ...
Amir Alimmohamadi +3 more
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