Results 41 to 50 of about 184,283 (297)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Educational policies and activities for preschool children: Reflections from the cultural-historical approach and activity theory [PDF]

, 2014
Educational activities employed with preschool children have significance in their development and preparation for school learning. For this reason, it is necessary to analyze the relationship established between educational policies and educational ...
Luis Quintanar-Rojas, González-Moreno, Claudia Ximena, Solovieva, Yulia, Yulia Solovieva, Claudia Ximena González-Moreno, Quintanar-Rojas, Luis   +5 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Ceramics from the scythian burial ground of Chineta-2 (Altai)

Поволжская археология
The article presents the results of the study of ceramics discovered during the study of barrows of the Scythian-Saka period at the Chineta 2 burial ground, located in the Krasnoshchyokovo district of the Altai Krai. The site contains signs of the burial
Dashkovskiy Petr K., Stepanova Nadezhda F.   +1 more
doaj   +1 more source

Digital Preservation:A New Approach to Protecting Historical and Cultural Towns and Villages

Contemporary Social Sciences, 2018
Digital technology has penetrated all aspects of modern life and is pushing society forward by profoundly changing the way people live and think.It can not only eternalize cultural heritage,but also allow relevant knowledge to be spread more quickly and ...
Liu Peilin
doaj   +1 more source

The Cultural Landscape & Heritage Paradox; Protection and Development of the Dutch Archeological-Historical Landscape and its European Dimension [PDF]

, 2010
To what extent can we know past and mainly invisible landscapes, and how we can use this still hidden knowledge for actual sustainable management of landscape’s cultural and historical values.
Kars, H., Wijnen, M., Bloemers, J.H.F., Valk, A.J.J., van der   +3 more
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Sokolny VII – a New Site of the Early Neolite of the Republic of Mari El

Поволжская археология
The article presents the results of a study of the Sokolny XVII camp-site (Republic of Mari El). The physical and geographical characteristics of the location of the site are given and a brief history of the study is given.
Kudashov Alexander S. , Andreev Konstantin M. , Vybornov Alexander A., Aleshinskaya Anna S., Vasilieva Irina N., Somov Anatoly V., Panteleeva Tatyana Y.   +6 more
doaj   +1 more source

The Models of Relationship between Training and Psyche development in Cultural-historical and Activity Approaches

Психологическая наука и образование (2007. Online), 2016
The possibility of referring of the psychological theories studying interrelation of training and mental development processes to this or that stage of scientific knowledge formation on the basis of studied objects types and corresponded determination ...
Pogozhina I.N.,
doaj   +1 more source