Results 51 to 60 of about 1,527,200 (314)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Ceramics from the scythian burial ground of Chineta-2 (Altai)
Поволжская археологияThe article presents the results of the study of ceramics discovered during the study of barrows of the Scythian-Saka period at the Chineta 2 burial ground, located in the Krasnoshchyokovo district of the Altai Krai. The site contains signs of the burial
Dashkovskiy Petr K. +1 more
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Digital Preservation:A New Approach to Protecting Historical and Cultural Towns and Villages
Contemporary Social Sciences, 2018 Digital technology has penetrated all aspects of modern life and is pushing society forward by profoundly changing the way people live and think.It can not only eternalize cultural heritage,but also allow relevant knowledge to be spread more quickly and ...
Liu Peilin
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Sokolny VII – a New Site of the Early Neolite of the Republic of Mari El
Поволжская археологияThe article presents the results of a study of the Sokolny XVII camp-site (Republic of Mari El). The physical and geographical characteristics of the location of the site are given and a brief history of the study is given.
Kudashov Alexander S. +6 more
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Психологическая наука и образование (2007. Online), 2016 The possibility of referring of the psychological theories studying interrelation of training and mental development processes to this or that stage of scientific knowledge formation on the basis of studied objects types and corresponded determination ...
Pogozhina I.N.,
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Методологические подходы в междисциплинарных исследованиях истории библиотечного дела
Библиосфера, 2011 The methodological approaches in interdisciplinary researches of library activities history - historical and cultural, regional, historical and library science are considered.
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Cultural-Historical Foundations of School Course in Biology
Психологическая наука и образование, 2020 The article analyzes the provisions of the cultural-historical psychology that serve as a theoretical and methodological basis for the practice of general education in biology.
Suchorukova L.N., Isaev E.I.
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