Results 91 to 100 of about 7,848,834 (290)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Holocaust and Russian Historical Culture. A Century-Long Perspective
, 2003 The article analyses the narrative structures in which the Holocaust has been situated in Russian historical ...
Lund University., Karlsson, Klas-Göran,
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Annual Report Kansas Historical Society, Inc. Fiscal Year 2013 Annual Report
, 2007 In 2006 two annual reports were issued: one covering the activities of the Historical Society as a state agency , and one covering the activities of the Kansas State Historical Society Inc.
Kansas State Historical Society
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Indiana Historical Society Constitution
Those signing the constitution for the IHS included such notable local citizens as Calvin Fletcher, William Conner, John Tipton, David Wallace, Noah Noble, and John DePauw.
Indiana Historical Society
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The Holocaust as a Problem of Historical Culture. Theoretical and Analytical Challenges
, 2003 The article analyses the theoretical and analytical problems related to historical culture, focusing on the ...
Lund University., Karlsson, Klas-Göran,
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ImagesThe article addresses the problem of narrativizing the past in a digital ego-documentary using the example of the game Cosmic Top Secret (Klassefilm, 2018), directed by Trine Laier.
Marcin Pigulak
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Palmetto Historical Commission-Historical timeline
This is an historical timeline of Palmetto, compiled by Palmetto Historical Commission.
Palmetto Historical Commission
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