Results 121 to 130 of about 277,480 (307)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Studia Humanitatis, 2016 The article analyses the philosophical and methodological problems of studying historical consciousness as a factor of demythologizing historical culture.
Ivanov Andrei Gennadiyevich +1 more
doaj
Other title: Kansas Preservation Plan
, 2011 application/pdf; Includes bibliographical references (Pages 18-21 [20-23 of 24])."This document is the result of a planning process initiated by the Kansas Historical Society's Cultural Resources Division (CRD) with input from a variety of state and
Kansas State Historical Society. Historic Preservation Office.
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Culture in Historical Narration
, 2020 The goal of the publication is to discuss the cultural dimension of historical narration. The subject of the consideration includes the following research issues: the humanities related to the subject matter of human and culture; relation of different ...
Czyrka, Marek
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The Proceedings of the South Carolina Historical Association [PDF]
, 1998 Annually, the association publishes a journal, The Proceedings, which consists of papers presented at the annual meeting. Barbarians as a Destabilizing Factor in the Late Roman Empire: The Case of Magnus Maximus by Walter Roberts, Graduate Student ...
South Carolina Historical Association
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Media Conscious Understanding of Historical Popular Culture
, 2021 This article focuses on popular historical culture, particularly on how the use of digital mediahas changed our engagements with historical culture. Popular historical culture is discussed asa cultural phenomenon that is present across all media. Because
Lähteenmäki, Ilkka
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
ReligionsModernity is characterised by a specific scientific paradigm based on binary logic. Neither freedom nor creativity have a place in this logical model. On the contrary, triadic logic enables rational consideration of an anthropological and social model ...
Teresa Aizpun
doaj +1 more source