Results 61 to 70 of about 277,480 (307)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Atentát na Heydricha ve filmu Anthropoid. Globální a lokální recepce minulosti || Heydrich's assassination in film. Global and local reception of the past [PDF]

open access: yesHistorie - Otázky - Problémy, 2018
Taking an example of an analysis of viewers’ comments on the film Anthropoid (2016, directed by Sean Ellis), on the local Czech portal csfd.cz and on the portal IMDB.com, opened to the global viewing community, shows some differences in the reception of ...
Jaroslav Pinkas
doaj  

Culture-led Regeneration in Historical and Cultural Areas

open access: yesCulture Unbound
Despite embracing various historical and cultural values, historical areas of Iran are experiencing massive changes in their functional, social and physical profiles, often without apt recognition of the role of culture in urban regeneration. This paper aims to examine the role of culture-led regeneration in enhancing the quality of a cultural and ...
Afsari Bajestani, Sepideh   +1 more
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Government environmental regulation and farmers' engagement in traditional folk practices: the mediating roles of ecological cognition and social norms

open access: yesFrontiers in Psychology
IntroductionAs an important carrier of cultural identity and community cohesion in rural Chinese society, traditional folk activities often generate tensions with modern ecological protection goals due to their resource-intensive characteristics.
Qing Wu   +4 more
doaj   +1 more source

Middle Paleolithic Site Sukhaya Mechёtka: the Renewal of Complex Investigations

open access: yesНижневолжский археологический вестник, 2020
The Sukhaya Mechёtka site, located on the northern outskirts of Volgograd, has attracted the attention of Paleolithic researchers since its discovery in 1951 by geologists A.I.Koptev and M.N. Grishchenko. The materials of the site - a collection of stone
Aleksander K. Otcherednoy   +9 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Online Surveillance in a Swedish Context: Between acceptance and resistance

open access: yesNordicom Review, 2020
Users of digital media leave traces that corporations and authorities can harvest, systematise, and analyse; on the societal level, an overall result is the emergence of a surveillance culture.
Cocq Coppélie   +3 more
doaj   +1 more source

Railway and grade: the historical construction of contemporary [PDF]

open access: yes, 1998
This thesis attempts to understand the role and meaning of occupational identity in the contemporary British railway industry. It examines the way in which culture change initiatives and programmes have explicitly targeted an older 'railroad culture ...
Strangleman, Tim
core  

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