Results 141 to 150 of about 2,231,122 (308)

The Roads To and From Serfdom [PDF]

open access: yes
The institution of slavery displays a puzzling historical pattern: it is found mostly at intermediate stages of agricultural development, in horticultural societies, and less frequently among hunter-gatherers and societies at more advanced agrarian ...
Nils-Petter Lagerlof
core   +3 more sources

Representations about the Future of State in Political Thought (Marxism, Anarchism, Liberalism)

open access: yesRUDN Journal of Political Science, 2012
In the given article the author states that the representatives of various directions of political thought, such as Marxism, anarchism and liberalism are in whole united in perception that the perfect society as the result of historical development will ...
A N Nesterenko
doaj  

European Acquisitions in the United States:Re-examining Olivetti-Underwood Fifty Years Later [PDF]

open access: yes
While Italy's catch-up in the course of the 20th century has been nothing short of extraordinary, it has failed to produce a large number of global business players.
Andrea Goldstein   +2 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Current Account Deficits in European Emerging Markets [PDF]

open access: yes
Many of the emerging market economies in Europe are presently running current account deficits which are quite high relative to any global or historical standard and are fundamentally unsustainable.
Robert Shelburne
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Historical Development of Environment Protection Laws in the State of Qatar

open access: yesمجلة الاجتهاد للدراسات القانونية والاقتصادية, 2020
Qatar is one of the countries which pay considerable attention to environment, and thus enacted several legislations and laws to safeguard environment and life from any sort of pollution and harm. In mid-70s of the twentieth-century, State of Qatar established the Supreme Council for Environment and Nature Reserves (SCENR) to set up general policies on
openaire   +1 more source

AN OPTION VALUE APPROACH TO VALUING PRESERVATION PROPERTIES [PDF]

open access: yes
There has been a recent trend towards purchasing land for farmland preservation, wildlife refuges, other conservation, and cultural and historical preservation.
McCluskey, Jill J.   +2 more
core   +1 more source

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