Results 41 to 50 of about 3,597 (292)

Review essay on David Laibman, Deep History: A Study in Social Evolution and Human Potential [PDF]

open access: yesThe Journal of Philosophical Economics, 2011
While historical materialism and evolutionism provide similar explanations and ideas regarding the cause of long-term social change, the two theories are rarely used in conjunction with one another. In Deep History,the author David Laibman addresses some
Altug Yalcintas
doaj  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Struggle for Objectivity: Gramsci’s Historical-Political Vistas on Science against the Background of Lenin’s Epistemology

open access: yesHoST, 2020
This contribution interprets the intertwined issues of science, epistemology, society, and politics in Gramsci’s Prison Notebooks as a culturalist approach to science that does not renounce objectivity.
Omodeo Pietro Daniel
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Pepijn Brandon, War, Capital and the Dutch State (1588-1795).

open access: yesBMGN: Low Countries Historical Review, 2017
Pepijn Brandon, War, Capital and the Dutch State (1588-1795) (Dissertatie Universiteit van Amsterdam 2013; Historical Materialism Book Series 101, Leiden: Brill, 2015, 447 pp., ill., isbn 978 900 422 814 6).
Oscar Gelderblom
doaj   +1 more source

Chinese organic materialism and modern science studies: Rethinking Joseph Needham’s legacy

open access: yesCultures of Science, 2020
Historian of science Joseph Needham argued in various papers and books that the philosophy of organic materialism that informed classical Chinese science not only nurtured Chinese discoveries in areas such as magnetic studies, but also obstructed the ...
Arun Bala
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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