Results 41 to 50 of about 4,140,050 (256)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The Epistemological Subject in Kant’s Philosophy: A Critical Reflection from the Standpoint of Dialectical and Historical Materialism

open access: yesRevista Filosofía UIS
the epistemological subject in Kant’s philosophy plays a crucial role in the development of epistemological theory. Based on the standpoint of dialectical materialism and historical materialism, this study offers a critical reflection on the ...
Vân Hạnh Nguyễn
doaj   +1 more source

Redeeming class under the lens of historical materialism

open access: yesRevista Mundos do Trabalho, 2020
Book review: MATTOS, Marcelo Badaró. A classe trabalhadora: de Marx ao nosso tempo. São Paulo: Boitempo, 2019.
Victor Pastore
doaj   +1 more source

Jacob A. Zumoff, The Communist International and US Communism, 1919-1929 (2014)

open access: yesArchivos de Historia del Movimiento Obrero y la Izquierda, 2016
Reseña de Jacob A. Zumoff, The Communist International and US Communism, 1919-1929, Leiden, Brill (Historical Materialism book series, 82), 2014, 443 pgs.
Hernán Camarero
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Les figures royales dans l’historiographie communiste

open access: yesRecherches, 2023
During the communist period, the first rulers of Greater Romania were an awkward, and later a taboo subject in a historiography that was characterised by historical materialism and anti-monarchism.
Irina Gridan
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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