Results 51 to 60 of about 2,047,244 (375)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Review essay on David Laibman, Deep History: A Study in Social Evolution and Human Potential [PDF]

open access: yesThe Journal of Philosophical Economics, 2011
While historical materialism and evolutionism provide similar explanations and ideas regarding the cause of long-term social change, the two theories are rarely used in conjunction with one another. In Deep History,the author David Laibman addresses some
Altug Yalcintas
doaj  

The Criticism of Materialism in Late Ottoman’s New Science of Kalām

open access: yesULUM, 2019
Materialism, which reduces the whole of existence as simply matter and its interactions, and respectively ignores the intervention of a divine being into the universe; it is often traced back to a time when philosophy was born. However, when we study the
Mehmet Bulğen
doaj   +1 more source

The meaning of materiality: reconsidering the materiality of Gramscian IR [PDF]

open access: yes, 2011
No description ...
Anderson   +47 more
core   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

El materialismo histórico de Sartre: el final de la teleología moderna / Sartre 's historical materialism: the end of modern teleology [PDF]

open access: yes, 2015
Resumen: En la modernidad se realizaron teleológias de la historia que desembocaron en filosofías de la historia como las de Hegel y Marx, estas teleologías estaban encaminadas hacia un proceso de  secularización.
Steinlen, Cedric
core   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel   +3 more
wiley   +1 more source

Lyubov Axelrod on Kant: Reflections on Marxist Discussions of the 1920s and 1930s in the USSR

open access: yesКантовский сборник
The authors attempt to look back on discussions of Marxist philosophy and historical materialism in this country without censoring, obfuscating, or simplifying issues in order to assess the prospects of their development.
Tatiana G. Shchedrina   +2 more
doaj   +1 more source

Philosofy as an element of national culture [PDF]

open access: yes, 2015
The report focuses on the role of philosophy in public culture, as well as the analysis of philosophy of the Soviet period. Shows directed evolution of nature and society, indicating the presence of self-regulatory processes.
Chumakov, V. A., Чумаков, В. А.
core  

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

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