Results 41 to 50 of about 10,071,074 (300)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Motivation im Fach Civilisation
Traduction et Langues, 2015 Motivation in Civilization This article aims to make a first and modest assessment of the teaching of civilization. It should be emphasized that today the learner has little contact with ancient times and that consequently it is difficult for him to ...
Abdesslam Bereksi Reguig
doaj
Cahiers Victoriens et Edouardiens, 2014 Walter Pater’s Marius the Epicurean (1885) may be seen as part of the subgenre of the all but forgotten Historical Novel of Early Christianity, which is represented by such lights as Newman, Kingsley, and Wiseman.
Jude Wright
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Metacritic Journal for Comparative Studies and Theory, 2023 The article proposes an analysis of the representations of the Tatars in two historical novels published in Poland and Romania, respectively, from the end of the 19th century and the beginning of the 20th century.
Andreea Mîrț
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Kansas State Historical Society Annual Report, 2018
, 2018 The Kansas State Historical Society became the Kansas Historical Society, a state agency, in 2007. The Kansas State Historical Society, Inc. is a private foundation.
Kansas Historical Society
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Kansas State Historical Society Annual Report, 2015
, 2015 The Kansas State Historical Society, Inc., doing business as the Kansas Historical Foundation, is an IRS determined 501(c)(3) non-profit and serves as the fund raising, fund management, membership, and retail organization for the Kansas Historical ...
Kansas State Historical Society
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source