Results 61 to 70 of about 220,864 (310)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Abduction : the writing of a historical novel

open access: yes, 2011
This is a practice-led project consisting of a historical novel Abduction and related exegesis.\ud \ud The novel is a third person intimate narrative set in the mid-nineteenth century and is based on actual events and persons caught up in, or furthering,
MacLeod, Mhairead Ellen
core  

A HISTORICAL NOVEL IN THE HISTORY TEACHING

open access: yes, 2021
U radu se prikazuje analiza povijesnih romana korištenjem povjesničarskih vještina koje učenici/čitatelji razvijaju tijekom nastave Povijesti. Odabiru se romani koji su kompatibilni sa sadržajima, temama i ishodima u kurikulumu Povijesti.
PEŠORDA, SUZANA
core  

Totalitarism, realism och historisk ängslighet

open access: yesTidskrift för Litteraturvetenskap, 2019
Totalitarianism, Realism and the Anxiety of History This essay examines the problem of totalitarian art and totalitarianism by studying the relationship between art, society and history in realism, both as a historical literary practice and as an ...
Tora Lane
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The historical novel

open access: yes, 1962
The Classical Form of the Historical Novel - Historical Novel and Historical Drama - The Historical Novel and the Crisis of Bourgeois - The Historical Novel of Democratic ...
Hannah Mitchell   +2 more
core  

A narrative analysis of Zeffirelli's and Stevenson's Jane Eyre [PDF]

open access: yes, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Letras/Inglês e Literatura Correspondente.The present study aims at analyzing two filmic adaptations from Charlotte Brontë's ...
Moraes, Rita de Cássia Eleutério de
core  

Antimodern cannibals. The 1799 of Francesco Mastriani

open access: yesFinzioni
Mastriani’s traditional classification as an author of social novels now seems overly restrictive. In some of his major works, he transforms his novels into a privileged space for exploring the complex relationships between history and fiction.
Elisa Chiocchetti
doaj   +1 more source

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