Results 41 to 50 of about 174,958 (266)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Maria Montessori in the Role of a Teacher
Edukacja Elementarna w Teorii i Praktyce, 2018 The essay analyses the figure of Maria Montessori as a teacher and the teaching that she conducted in her career. A historical perspective is adopted, with reference to some fundamental moments in Montessori’s teaching life, described with the help of ...
Paola Trabalzini
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Cuadernos de Administración, 2010 En la primera década del siglo XXI, los conceptos de responsabilidad corporativa y la noción de desarrollo sostenible han sido ampliamente difundidos tanto en los círculos de investigadores como en los de profesionales de la gestión y de la ...
Emmanuel Raufflet
doaj
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Clinical Optometry, 2020 Rayishnee Pillay,1 Rekha Hansraj,2 Nishanee Rampersad2 1University of KwaZulu-Natal, Durban, South Africa; 2Discipline of Optometry, University of KwaZulu-Natal, Durban, South AfricaCorrespondence: Rayishnee PillayUniversity of KwaZulu-Natal, University ...
Pillay R, Hansraj R, Rampersad N
doaj
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Economic growth in Western Europe 1870-1957
PSL Quarterly Review, 2014 The article puts Europe’s post-war experience into historical perspective in order to provide some criteria for measuring post-war economic performance.
A. MADDISON
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source