Results 51 to 60 of about 174,958 (266)
CAPE VERDE AND ITS ROCKS: A HISTORICAL PERSPECTIVE [PDF]
Geochimica Brasiliensis, 2012 One of the first geological investigations in Cape Verde was made by Charles Darwin in1832 in the island of Santiago. Darwin was preceded by J.S. Feijó (Brava and Fogo islands,1784-85), and succeeded by Sainte-Claire Deville (Fogo island,
A. Soares de Andrade
doaj
Visualization of International Energy Policy Research
Energies, 2016 The complexity of policy decision making is well recognized. It is not clear, however, what role academic policy research has played in influencing the directions of policy outcomes and how the research has intertwined with notable issues globally. Given
Xiaoling Wang +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Essiac: An historical perspective
Canadian Oncology Nursing Journal, 1997 It is believed that over one-half of people diagnosed with cancer will at some point use an unconventional therapy (Hopkins & Brigden, 1991). In light of this, nurses have a professional responsibility to learn about unconventional therapies (Fletcher, 1992) so they can help their patients make informed choices.
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
SocietiesThis concept paper introduces the Contextual Critical Historical Inquiry and Analysis (CCHIA) framework—a critical synthesis tool designed to advance historical contextual inquiry in urban studies.
Hisham Abusaada, Abeer Elshater
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Cabás, 2020 Treinta y tres años, ocho leyes; una cada cuatro años en una media aritmética. Esta situación sirve para ofrecer una explicación de lo que está aconteciendo en España dentro del panorama educativo actual, donde paradigmas objetivos como los informes PISA
Pérez Lorenzo, J.F. +2 more
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source